Kaplan-Meier estimates for TT and OS by risk factor
| Biomarker . | TT . | OS . | ||
|---|---|---|---|---|
| Median, y . | 95% CI . | Median, y . | 95% CI . | |
| Methylation, <20% | 2.9 | 2.0-3.3 | 9.1 | 8.0-11.1 |
| Methylation, ≥20% | 6.5 | 5.4-9.0 | 17.5 | 16.7-NR |
| M-IGHV | 6.3 | 4.5-8.0 | 16.7 | 12.1-22.7 |
| U-IGHV | 2.9 | 2.1-3.4 | 9.1 | 8.0-11.0 |
| CD38− | 4.4 | 3.7-5.6 | 12.0 | 9.1-16.7 |
| CD38+ | 2.8 | 1.9-3.4 | 9.7 | 8.4-12.2 |
| ZAP-70− | 5.5 | 4.2-6.9 | 16.7 | 12.1-22.7 |
| ZAP-70+ | 2.1 | 1.7-2.9 | 8.8 | 7.8-9.9 |
| Biomarker . | TT . | OS . | ||
|---|---|---|---|---|
| Median, y . | 95% CI . | Median, y . | 95% CI . | |
| Methylation, <20% | 2.9 | 2.0-3.3 | 9.1 | 8.0-11.1 |
| Methylation, ≥20% | 6.5 | 5.4-9.0 | 17.5 | 16.7-NR |
| M-IGHV | 6.3 | 4.5-8.0 | 16.7 | 12.1-22.7 |
| U-IGHV | 2.9 | 2.1-3.4 | 9.1 | 8.0-11.0 |
| CD38− | 4.4 | 3.7-5.6 | 12.0 | 9.1-16.7 |
| CD38+ | 2.8 | 1.9-3.4 | 9.7 | 8.4-12.2 |
| ZAP-70− | 5.5 | 4.2-6.9 | 16.7 | 12.1-22.7 |
| ZAP-70+ | 2.1 | 1.7-2.9 | 8.8 | 7.8-9.9 |
M-IGHV, IGHV mutated; NR, not reached; U-IGHV, IGHV unmutated.