Table 1

Data sources

Data setSample numberCell typesReference
Normal blood and BM populations  
 GSE42519 34 HSC, MPP, CMP, MEP, GMP, early PM, late PM, MY, MM, BC, PMN This study 
 GSE17054 HSC Majeti et al19  
 GSE19599 GMP, MEP Andersson et al20  
 GSE11864 Monocytes Hu et al21  
 E-MEXP-1242 Monocytes Wildenberg et al22  
 Total 44   
AML patient samples    
 GSE13159 191 t(8;21), inv(16), t(15;17), t(11q23), complex Haferlach et al 
 GSE14468 526 MDS:-5/7(q), −9q, 11q23, 8, complex; AML: NK, complex, inv(3q), inv(16), t(15;17), t(6;9), t(8;21), t(9;22) Wouters et al11  
 GSE15434 251 NK-AML Kohlmann et al,Klein et al12  
 TCGA 183 Various genetic aberrations, including t(8;21), inv(16), t(15;17), t(11q23), complex Cancer Genome Atlas Research Network13  
 GSE6891 91 Various genetic aberrations, including t(8;21), inv(16), t(15;17), t(11q23) de Jonge et al18  
 GSE12417 79 NK-AML Metzeler et al15  
 Total 1321   
Data setSample numberCell typesReference
Normal blood and BM populations  
 GSE42519 34 HSC, MPP, CMP, MEP, GMP, early PM, late PM, MY, MM, BC, PMN This study 
 GSE17054 HSC Majeti et al19  
 GSE19599 GMP, MEP Andersson et al20  
 GSE11864 Monocytes Hu et al21  
 E-MEXP-1242 Monocytes Wildenberg et al22  
 Total 44   
AML patient samples    
 GSE13159 191 t(8;21), inv(16), t(15;17), t(11q23), complex Haferlach et al 
 GSE14468 526 MDS:-5/7(q), −9q, 11q23, 8, complex; AML: NK, complex, inv(3q), inv(16), t(15;17), t(6;9), t(8;21), t(9;22) Wouters et al11  
 GSE15434 251 NK-AML Kohlmann et al,Klein et al12  
 TCGA 183 Various genetic aberrations, including t(8;21), inv(16), t(15;17), t(11q23), complex Cancer Genome Atlas Research Network13  
 GSE6891 91 Various genetic aberrations, including t(8;21), inv(16), t(15;17), t(11q23) de Jonge et al18  
 GSE12417 79 NK-AML Metzeler et al15  
 Total 1321   

Description and origin of all microarray data sets used in this study, including normal blood and BM populations and AML patient samples. All samples were run on the HG-U133 Plus 2.0 Array Affymetrix platform.

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