Table 4

Gene expression average fold-change in the whole-blood mRNA relative to total kidney lysate (input)

GeneExpressionFold-change ± SEMRangeP value
Cdh5 Endothelial 0.08 ± 0.01 0.074-0.095 <7.4 × 10−5 
Tek Endothelial 0.002 ± 0.001 0.007-0.010 <2.1 × 10−5 
Vcam1 Endothelial 0.003 ± 0.004 0.001-0.009 <3.2 × 10−3 
Vwf Endothelial/megakaryocyte 248.92 ± 15.56 233.2-264.9 <3.3 × 10−9 
F5 Hepatic/megakaryocyte 73.41 ± 3.15 70.3-76.6 <1.5 × 10−5 
F8 0.02 ± 0.01 0.011-0.029 <1.5 × 10−4 
GeneExpressionFold-change ± SEMRangeP value
Cdh5 Endothelial 0.08 ± 0.01 0.074-0.095 <7.4 × 10−5 
Tek Endothelial 0.002 ± 0.001 0.007-0.010 <2.1 × 10−5 
Vcam1 Endothelial 0.003 ± 0.004 0.001-0.009 <3.2 × 10−3 
Vwf Endothelial/megakaryocyte 248.92 ± 15.56 233.2-264.9 <3.3 × 10−9 
F5 Hepatic/megakaryocyte 73.41 ± 3.15 70.3-76.6 <1.5 × 10−5 
F8 0.02 ± 0.01 0.011-0.029 <1.5 × 10−4 

To evaluate the potential contribution of blood contamination to transcript levels of endothelial-specific genes, the tissue lysates of kidney samples were set as a reference and the ΔCt values of individual blood samples (n = 4) were related to the mean ΔCt of the reference group.

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