Table 1 Immunoglobulins rescued from... | American Society of Hematology

Table 1

Immunoglobulins rescued from lymphomas of HCV-infected patients do not react with HCV proteins

Patient	Isotype	Diagnosis	Lymphoma response to antiviral therapy	V_H	V_L	Accession # V_H/V_L	HCV genotype	E2₆₆₁	J6E2	E1E2	NS + Core
101	IgM/k	DLBCL	ND	V_H1-69	V_k3-20	KF895775/6	ND	Neg	ND	ND	ND
102	IgM/k	FL	ND	V_H3-48	V_k1-39	KF895777/8	ND	Neg	ND	ND	ND
103	Ig*/k	MZL	ND	V_H4-59	V_k3-20	KF895779/80	ND	Neg	ND	ND	ND
104	IgM/k	DLBCL	ND	V_H1-69	V_k1D-16	KF895781/2	ND	Neg	ND	ND	ND
105	IgM/k	DLBCL	ND	V_H1-69	V_k3-20	KF895783/4	ND	Neg	ND	ND	ND
106	IgM/k	NHL	ND	V_H4-59	V_k3-15	KF895785/6	ND	Neg	ND	ND	ND
107	IgM/k	NA	ND	V_H3-21	V_k1-39	KF895787/8	ND	Neg	ND	ND	ND
108	IgM/k	NA	ND	V_H4-59	V_k3-15	KF895789/90	ND	Neg	Neg	Neg	Neg
109	IgM/k	NA	ND	V_H4-34	V_k3-20	KF895791/2	ND	Neg	Neg	Neg	Neg
110	IgM/k	NA	ND	V_H4-59	V_k3-20	KF895793/4	ND	Neg	Neg	Neg	Neg
111	IgG/k	NA	ND	V_H1-02	V_k2-30	KF895795/6	ND	Neg	Neg	Neg	Neg
112	IgM/k	NA	ND	V_H4-34	V_k3-20	KF895797/8	ND	Neg	Neg	Neg	Neg
121	IgM/k	MALT MZL	Yes	V_H1-69	V_k3-20	KF895799/800	2a/2c	Neg	Neg	Neg	Neg
122	IgM/k	SMZL	No	V_H4-59	V_k3D-15	KF895801/2	1b	Neg	Neg	Neg	Neg
123	IgM/k	SMZL	Yes	V_H1-69	V_k3-20	KF895803/4	2a/2c	Neg	Neg	Neg	Neg
124	IgM/k	MALT MZL	Yes	V_H4-30	V_k3-15	KF895805/6	2a/2c	Neg	Neg	Neg	Neg
125	IgM/k	SMZL	Yes	V_H3-30	V_k1-8	KF895807/8	2a/2c	Neg	Neg	Neg	Neg
126	IgM/k	MALT MZL	Yes	V_H1-69	V_k3-20	KF895809/10	1b	Neg	Neg	Neg	Neg
127	IgM/k	NHL	No	V_H1-69	V_k3-20	KF895811/2	1b	Neg	Neg	Neg	Neg

Patient	Isotype	Diagnosis	Lymphoma response to antiviral therapy	V_H	V_L	Accession # V_H/V_L	HCV genotype	E2₆₆₁	J6E2	E1E2	NS + Core
101	IgM/k	DLBCL	ND	V_H1-69	V_k3-20	KF895775/6	ND	Neg	ND	ND	ND
102	IgM/k	FL	ND	V_H3-48	V_k1-39	KF895777/8	ND	Neg	ND	ND	ND
103	Ig*/k	MZL	ND	V_H4-59	V_k3-20	KF895779/80	ND	Neg	ND	ND	ND
104	IgM/k	DLBCL	ND	V_H1-69	V_k1D-16	KF895781/2	ND	Neg	ND	ND	ND
105	IgM/k	DLBCL	ND	V_H1-69	V_k3-20	KF895783/4	ND	Neg	ND	ND	ND
106	IgM/k	NHL	ND	V_H4-59	V_k3-15	KF895785/6	ND	Neg	ND	ND	ND
107	IgM/k	NA	ND	V_H3-21	V_k1-39	KF895787/8	ND	Neg	ND	ND	ND
108	IgM/k	NA	ND	V_H4-59	V_k3-15	KF895789/90	ND	Neg	Neg	Neg	Neg
109	IgM/k	NA	ND	V_H4-34	V_k3-20	KF895791/2	ND	Neg	Neg	Neg	Neg
110	IgM/k	NA	ND	V_H4-59	V_k3-20	KF895793/4	ND	Neg	Neg	Neg	Neg
111	IgG/k	NA	ND	V_H1-02	V_k2-30	KF895795/6	ND	Neg	Neg	Neg	Neg
112	IgM/k	NA	ND	V_H4-34	V_k3-20	KF895797/8	ND	Neg	Neg	Neg	Neg
121	IgM/k	MALT MZL	Yes	V_H1-69	V_k3-20	KF895799/800	2a/2c	Neg	Neg	Neg	Neg
122	IgM/k	SMZL	No	V_H4-59	V_k3D-15	KF895801/2	1b	Neg	Neg	Neg	Neg
123	IgM/k	SMZL	Yes	V_H1-69	V_k3-20	KF895803/4	2a/2c	Neg	Neg	Neg	Neg
124	IgM/k	MALT MZL	Yes	V_H4-30	V_k3-15	KF895805/6	2a/2c	Neg	Neg	Neg	Neg
125	IgM/k	SMZL	Yes	V_H3-30	V_k1-8	KF895807/8	2a/2c	Neg	Neg	Neg	Neg
126	IgM/k	MALT MZL	Yes	V_H1-69	V_k3-20	KF895809/10	1b	Neg	Neg	Neg	Neg
127	IgM/k	NHL	No	V_H1-69	V_k3-20	KF895811/2	1b	Neg	Neg	Neg	Neg

DLBCL, diffuse large B-cell lymphoma; FL, follicular lymphoma; Ig*, undetermined heavy chain; MALT, mucosa-associated lymphoid tissue; MZL, marginal zone lymphoma; NA, not available; ND, not done; Neg, negative; NS + Core, HCV nonstructural + core proteins; SMZL, splenic marginal zone lymphoma.

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