Clonogenic assay post–PEG-IFN-α-2a therapy
MPN . | JAK2V617F mutant . | Response . | Number of total colonies (number of erythroid colonies)* . | |
---|---|---|---|---|
+ EPO . | – EPO . | |||
PV | Yes | CMR | 12 (3) | 16 (4) |
PV | Yes | CMR | 2 | 5 (2) |
ET | Yes | CMR | 14 (3) | 15 (3) |
PV | Yes | CMR | 26 (5) | 22 (6) |
PV | Yes | CMR | 21 (4) | 22 (5) |
ET | Yes | CMR | 9 (3) | 11 (5) |
ET | Yes | mMR | 12 (2) | 2 |
PV | Yes | PMR | 21 (7) | 15 (3) |
PV | No | CHR | 3 (1) | 1 (1) |
ET | No | CHR | 16 (3) | 3 (1) |
ET | No | CHR | 15 (2) | 15 (3) |
ET | No | PHR | 32 (9) | 30 (6) |
MPN . | JAK2V617F mutant . | Response . | Number of total colonies (number of erythroid colonies)* . | |
---|---|---|---|---|
+ EPO . | – EPO . | |||
PV | Yes | CMR | 12 (3) | 16 (4) |
PV | Yes | CMR | 2 | 5 (2) |
ET | Yes | CMR | 14 (3) | 15 (3) |
PV | Yes | CMR | 26 (5) | 22 (6) |
PV | Yes | CMR | 21 (4) | 22 (5) |
ET | Yes | CMR | 9 (3) | 11 (5) |
ET | Yes | mMR | 12 (2) | 2 |
PV | Yes | PMR | 21 (7) | 15 (3) |
PV | No | CHR | 3 (1) | 1 (1) |
ET | No | CHR | 16 (3) | 3 (1) |
ET | No | CHR | 15 (2) | 15 (3) |
ET | No | PHR | 32 (9) | 30 (6) |
Number of total colonies from cells grown with EPO and without EPO is displayed. Of the total number of colonies, the colonies that are erythroid colonies are shown in parentheses.