Table 1 Impact of DDAVP on platelet... | American Society of Hematology

Table 1

Impact of DDAVP on platelet aggregation (n=10)

		Baseline		4 hours after DDAVP
Agonist/ concentration	Parameter	Median	IQR	Median	IQR	P*
ADP
Low	Aggregation at 3 min (%)	28	16-48	21	10-41	.922
Medium		52	39-71	61	45-77	.625
High		73	57-81	75	68-84	.846
Collagen, μg/mL
1.5	Lag phase, s	92	86-102	96	86-130	.492
3.0		70	67-85	69	66-88	.193
4.0		65	58-74	61	57-79	1.000
1.5	Aggregation at 3 min (%)	66	46-82	74	22-82	.322
3.0		81	73-88	82	75-85	.846
4.0		81	73-90	83	77-86	.557
Arachidonate, mM
2	Lag phase, s	44	35-73	44	31-70	.770
2	Aggregation at 3 min (%)	70	30-82	71	57-80	1.000
Ristocetin, mg/mL
0.75	Aggregation at 3 min (%)	6	4-7	6	4-7	.322
1.50		92	91-94	96	90-98	.322

		Baseline		4 hours after DDAVP
Agonist/ concentration	Parameter	Median	IQR	Median	IQR	P*
ADP
Low	Aggregation at 3 min (%)	28	16-48	21	10-41	.922
Medium		52	39-71	61	45-77	.625
High		73	57-81	75	68-84	.846
Collagen, μg/mL
1.5	Lag phase, s	92	86-102	96	86-130	.492
3.0		70	67-85	69	66-88	.193
4.0		65	58-74	61	57-79	1.000
1.5	Aggregation at 3 min (%)	66	46-82	74	22-82	.322
3.0		81	73-88	82	75-85	.846
4.0		81	73-90	83	77-86	.557
Arachidonate, mM
2	Lag phase, s	44	35-73	44	31-70	.770
2	Aggregation at 3 min (%)	70	30-82	71	57-80	1.000
Ristocetin, mg/mL
0.75	Aggregation at 3 min (%)	6	4-7	6	4-7	.322
1.50		92	91-94	96	90-98	.322

Statistics: Wilcoxon signed rank test.