Table 3

Comparison of response rate (PR or better) according to baseline characteristics

ValuePatients, n≥PR, n (%) [90% CI]P*
Baseline characteristics     
 ISS disease stage at diagnosis I 17 12 (71) [48-88] .99 
 II/III 31 21 (68) [52-81]  
 Durie-Salmon disease stage at diagnosis I 9 6 (67) [35-90] .99 
 II/III 54 34 (63) [51-74]  
 Current disease status Relapsed 37 23 (62) [47-76] .80 
 Relapsed/refractory 27 18 (67) [49-81]  
 β2-microglobulin, mg/L <3.5 32 20 (63) [47-77] .99 
 ≥3.5 29 19 (66) [49-80]  
 Albumin, g/dL <3.5 9 5 (56) [25-83] .71 
 ≥3.5 54 36 (67) [55-77]  
 Hemoglobin, g/dL <12 42 25 (60) [46-72] .41 
 ≥12 22 16 (73) [53-87]  
 Serum calcium, g/dL <10 53 34 (64) [52-75] .99 
 10-12 11 7 (64) [35-87]  
 Elevated LDH No 49 32 (65) [53-77] .73 
 Yes 10 6 (60) [30-85]  
Cytogenetics†     
 Abnormal cytogenetics by metaphase karyotyping Yes 16 9 (56) [33-77] .55 
No 44 29 (66) [53-78]  
 Presence of del13/13q by FISH Yes 23 11 (48) [30-67] .06 
 No 18 14 (78) [56-92]  
 Presence of del17p by FISH Yes 8 4 (50) [19-81] .42 
 No 28 19 (68) [51-82]  
 Presence of t(4;14) by FISH Yes 4 2 (50) [10-90] .60 
 No 33 22 (67) [51-80]  
 Presence of del17p and/or t(4;14) by FISH Yes 10 5 (50) [22-78] .43 
 No 23 16 (70) [50-85]  
ValuePatients, n≥PR, n (%) [90% CI]P*
Baseline characteristics     
 ISS disease stage at diagnosis I 17 12 (71) [48-88] .99 
 II/III 31 21 (68) [52-81]  
 Durie-Salmon disease stage at diagnosis I 9 6 (67) [35-90] .99 
 II/III 54 34 (63) [51-74]  
 Current disease status Relapsed 37 23 (62) [47-76] .80 
 Relapsed/refractory 27 18 (67) [49-81]  
 β2-microglobulin, mg/L <3.5 32 20 (63) [47-77] .99 
 ≥3.5 29 19 (66) [49-80]  
 Albumin, g/dL <3.5 9 5 (56) [25-83] .71 
 ≥3.5 54 36 (67) [55-77]  
 Hemoglobin, g/dL <12 42 25 (60) [46-72] .41 
 ≥12 22 16 (73) [53-87]  
 Serum calcium, g/dL <10 53 34 (64) [52-75] .99 
 10-12 11 7 (64) [35-87]  
 Elevated LDH No 49 32 (65) [53-77] .73 
 Yes 10 6 (60) [30-85]  
Cytogenetics†     
 Abnormal cytogenetics by metaphase karyotyping Yes 16 9 (56) [33-77] .55 
No 44 29 (66) [53-78]  
 Presence of del13/13q by FISH Yes 23 11 (48) [30-67] .06 
 No 18 14 (78) [56-92]  
 Presence of del17p by FISH Yes 8 4 (50) [19-81] .42 
 No 28 19 (68) [51-82]  
 Presence of t(4;14) by FISH Yes 4 2 (50) [10-90] .60 
 No 33 22 (67) [51-80]  
 Presence of del17p and/or t(4;14) by FISH Yes 10 5 (50) [22-78] .43 
 No 23 16 (70) [50-85]  
*

Fisher’s exact P value.

†

Response rate not assessed according to presence/absence of t(14;16) because data were available in only 13 patients (unknown status in 51 patients).

View Large
Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal