Nonoverlapping classification of primary molecular cytogenetic abnormalities in MM
| FISH abnormality . | Frequency (%) (N = 484) . |
|---|---|
| Trisomy(ies) without IgH abnormality | 201 (42) |
| IgH abnormality without trisomy(ies) | 146 (30) |
| t(11;14) | 74 (15) |
| t(4;14) | 28 (6) |
| t(14;16) | 19 (4) |
| t(14;20) | 1 (<1) |
| Unknown partner/deletion of IgH region | 24 (5) |
| IgH abnormality with trisomy(ies) | 74 (15) |
| t(11;14) | 12 (3) |
| t(4;14) | 19 (4) |
| t(14;16) | 5 (1) |
| t(6;14) | 3 (<1) |
| Unknown partner/deletion of IgH region | 35 (7) |
| Monosomy 14 in absence of IgH translocations or trisomy(ies) | 22 (4.5) |
| Other cytogenetic abnormalities in absence of IgH translocations or trisomy(ies) or monosomy 14* | 26 (5.5) |
| Normal | 15 (3) |
| FISH abnormality . | Frequency (%) (N = 484) . |
|---|---|
| Trisomy(ies) without IgH abnormality | 201 (42) |
| IgH abnormality without trisomy(ies) | 146 (30) |
| t(11;14) | 74 (15) |
| t(4;14) | 28 (6) |
| t(14;16) | 19 (4) |
| t(14;20) | 1 (<1) |
| Unknown partner/deletion of IgH region | 24 (5) |
| IgH abnormality with trisomy(ies) | 74 (15) |
| t(11;14) | 12 (3) |
| t(4;14) | 19 (4) |
| t(14;16) | 5 (1) |
| t(6;14) | 3 (<1) |
| Unknown partner/deletion of IgH region | 35 (7) |
| Monosomy 14 in absence of IgH translocations or trisomy(ies) | 22 (4.5) |
| Other cytogenetic abnormalities in absence of IgH translocations or trisomy(ies) or monosomy 14* | 26 (5.5) |
| Normal | 15 (3) |
These included primarily monosomy 13 and p53 abnormalities.