Table 1 Most frequent recurrently... | American Society of Hematology

Table 1

Most frequent recurrently affected regions detected in 64 ALCL samples

Lesion/Cytoband	Start*	Size, kb*	RefSeq genes†	ALCL %	ALK⁻ALCL %	ALK⁺ALCL %	P
Losses
17p13.3-p12	526	11 747.22	>20 (TP53)	25	42	9	.002
6q21	105 944 900	951.75	ATG5, PRDM1	19	56	6	<.001
13q32.3-q33.3	99 090 837	9349.42	>20	16	23	9	ns
16q23.2	78 371 498	11 642	MAF, WWOX	16	29	3	.004
Gains
1q	121 344 093	127 880.29	>20	23	32	15	ns
8q24.22	133 799 280	919.4	NDRG1, PHF20L1, SLA, ST3GAL1, TG, WISP1	17	23	12	ns

Lesion/Cytoband	Start*	Size, kb*	RefSeq genes†	ALCL %	ALK⁻ALCL %	ALK⁺ALCL %	P
Losses
17p13.3-p12	526	11 747.22	>20 (TP53)	25	42	9	.002
6q21	105 944 900	951.75	ATG5, PRDM1	19	56	6	<.001
13q32.3-q33.3	99 090 837	9349.42	>20	16	23	9	ns
16q23.2	78 371 498	11 642	MAF, WWOX	16	29	3	.004
Gains
1q	121 344 093	127 880.29	>20	23	32	15	ns
8q24.22	133 799 280	919.4	NDRG1, PHF20L1, SLA, ST3GAL1, TG, WISP1	17	23	12	ns

P values were calculated between ALK⁺ALCL and ALK⁻ALCL frequencies.

ns, not significant.

Numbering according to Genome Reference Consortium Human Build 37 (GRCh37) (hg19).

According to the NCBI RefSeq database.