Table 2

Comparisons of SF-36 scale scores between patients transplanted for thalassemia and matched controls from the general population

SF-36 scalesTransplanted patients, mean (SD)Matched control group, mean (SD)Mean difference* (95% CI)P value
Physical health 
 Physical functioning 92.7 (14.1) 92.0 (15.3) −2.6 (−7.1; 1.9) .250 
 Role physical 94.5 (10.4) 88.8 (26.2) 3.1 (−3.1; 9.2) .324 
 Bodily pain 84.5 (23.6) 79.1 (24.1) −0.2 (−7.3; 7.0) .965 
 General health 69.9 (24.1) 72.2 (17.5) −8.9 (−15.0; 2.7)† .005‡ 
 PCS 53.0 (6.4) 53.2 (7.4) −2.1 (−4.1; 0.0) .05 
Mental health 
 Vitality 69.9 (19.5) 67.5 (16.5) −1.9 (−7.3; 3.6) .499 
 Social functioning 82.6 (23.6) 78.2 (20.2) 0.7 (−6.2; 7.5) .851 
 Role emotional 92.1 (14.3) 82.9 (30.6) 7.0 (−0.5; 14.5) .068 
 Mental health 77.3 (17.5) 70.3 (16.6) 4.9 (−0.3; 10.1) .065 
 MCS 54.1 (8.3) 51.0 (8.5) 2.0 (−0.6; 4.7) .127 
SF-36 scalesTransplanted patients, mean (SD)Matched control group, mean (SD)Mean difference* (95% CI)P value
Physical health 
 Physical functioning 92.7 (14.1) 92.0 (15.3) −2.6 (−7.1; 1.9) .250 
 Role physical 94.5 (10.4) 88.8 (26.2) 3.1 (−3.1; 9.2) .324 
 Bodily pain 84.5 (23.6) 79.1 (24.1) −0.2 (−7.3; 7.0) .965 
 General health 69.9 (24.1) 72.2 (17.5) −8.9 (−15.0; 2.7)† .005‡ 
 PCS 53.0 (6.4) 53.2 (7.4) −2.1 (−4.1; 0.0) .05 
Mental health 
 Vitality 69.9 (19.5) 67.5 (16.5) −1.9 (−7.3; 3.6) .499 
 Social functioning 82.6 (23.6) 78.2 (20.2) 0.7 (−6.2; 7.5) .851 
 Role emotional 92.1 (14.3) 82.9 (30.6) 7.0 (−0.5; 14.5) .068 
 Mental health 77.3 (17.5) 70.3 (16.6) 4.9 (−0.3; 10.1) .065 
 MCS 54.1 (8.3) 51.0 (8.5) 2.0 (−0.6; 4.7) .127 
*

Mean differences adjusted for age, gender, education, marital status, and comorbidity.

†

Exceeds minimally important difference (8 points for SF-36 scales and 2 points for PCS and MCS scales).

‡

Statistically significant after Bonferroni’s correction (adjusted α = 0.05/8 = 0.00625).

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