Summary of induction toxicities among 586 adult patients with AML
| . | DA+GO (n = 292) . | DA (n = 294) . | ||
|---|---|---|---|---|
| Patients . | % . | Patients . | % . | |
| Any fatal toxicity | 16 | 5 | 4 | 1 |
| Infection and/or febrile neutropenia | 5 | 2 | ||
| Central nervous system hemorrhage | 4 | 1 | ||
| Acute respiratory distress syndrome, dyspnea | 3 | 0 | ||
| Lung hemorrhage | 2 | 0 | ||
| Transfusion related acute lung injury with infection and central nervous system hemorrhage | 1 | 0 | ||
| Liver dysfunction | 1 | 0 | ||
| Other | 0 | 1 | ||
| Any grade 4+ nonhematologic | 61 | 21 | 36 | 12 |
| Any grade 3+ nonhematologic | 236 | 81 | 244 | 83 |
| . | DA+GO (n = 292) . | DA (n = 294) . | ||
|---|---|---|---|---|
| Patients . | % . | Patients . | % . | |
| Any fatal toxicity | 16 | 5 | 4 | 1 |
| Infection and/or febrile neutropenia | 5 | 2 | ||
| Central nervous system hemorrhage | 4 | 1 | ||
| Acute respiratory distress syndrome, dyspnea | 3 | 0 | ||
| Lung hemorrhage | 2 | 0 | ||
| Transfusion related acute lung injury with infection and central nervous system hemorrhage | 1 | 0 | ||
| Liver dysfunction | 1 | 0 | ||
| Other | 0 | 1 | ||
| Any grade 4+ nonhematologic | 61 | 21 | 36 | 12 |
| Any grade 3+ nonhematologic | 236 | 81 | 244 | 83 |