Explanatory power of baseline variables to predict OS
| Model . | Variation in survival (r2) . | IDI (95% CI)* . |
|---|---|---|
| Base clinical model (age, risk group, ECOG score, prior MDS, hemoglobin, creatinine > 1.3) | 0.20 | |
| +Comorbidity (HCT-CI score > 1) | 0.21 | 0.01 (0.00-0.08) |
| +Impaired objective PF (SPPB score < 9) | 0.26 | 0.05 (0.00-0.16) |
| +Cognitive function (3MS < 77) | 0.32 | 0.06 (0.00-0.16) |
| Model . | Variation in survival (r2) . | IDI (95% CI)* . |
|---|---|---|
| Base clinical model (age, risk group, ECOG score, prior MDS, hemoglobin, creatinine > 1.3) | 0.20 | |
| +Comorbidity (HCT-CI score > 1) | 0.21 | 0.01 (0.00-0.08) |
| +Impaired objective PF (SPPB score < 9) | 0.26 | 0.05 (0.00-0.16) |
| +Cognitive function (3MS < 77) | 0.32 | 0.06 (0.00-0.16) |
IDI, Integrated Discrimination Improvement.
95% CI is based on 1000 bootstrap replicate samples