MDS patient characteristics and response to miR-21 inhibition
N . | Age/Sex . | WBC (103/mL) . | Hgb (g/dL) . | Plt (103/mL) . | Subtype . | Cytogenetics . | Colonies post treatment with mismatched control . | Colonies post treatment with miR-21 inhibitor . | ||
---|---|---|---|---|---|---|---|---|---|---|
BFU-E . | CFU-GM . | BFU-E . | CFU-GM . | |||||||
1 | 63/M | 1.2 | 9 | 14 | RCMD | +11 | 204 | 12 | 259 | 24 |
2 | 79/f | 2.9 | 9.6 | 29 | RAEB | −7q | 22 | 4 | 26 | 5 |
3 | 68/F | 3.5 | 9.3 | 35 | RAEB | −5q, −18 | 20 | 37 | 49 | 46 |
4 | 70/M | 18.2 | 8.5 | 84 | RAEB | Nml | 91 | 93 | 121 | 86 |
5 | 69/F | 5.2 | 8.8 | 75 | RCMD | Nml | 62 | 26 | 98 | 25 |
N . | Age/Sex . | WBC (103/mL) . | Hgb (g/dL) . | Plt (103/mL) . | Subtype . | Cytogenetics . | Colonies post treatment with mismatched control . | Colonies post treatment with miR-21 inhibitor . | ||
---|---|---|---|---|---|---|---|---|---|---|
BFU-E . | CFU-GM . | BFU-E . | CFU-GM . | |||||||
1 | 63/M | 1.2 | 9 | 14 | RCMD | +11 | 204 | 12 | 259 | 24 |
2 | 79/f | 2.9 | 9.6 | 29 | RAEB | −7q | 22 | 4 | 26 | 5 |
3 | 68/F | 3.5 | 9.3 | 35 | RAEB | −5q, −18 | 20 | 37 | 49 | 46 |
4 | 70/M | 18.2 | 8.5 | 84 | RAEB | Nml | 91 | 93 | 121 | 86 |
5 | 69/F | 5.2 | 8.8 | 75 | RCMD | Nml | 62 | 26 | 98 | 25 |
WBC, white blood cells; plt, platelets; Hgb, hemoglobin.