Shorter-term success rates at 6 months, according to risk groups at second-line treatment
. | . | Success rates at 6 mo . | |||
---|---|---|---|---|---|
Risk group* . | N (%) . | FFS . | FFS + PDN ≤0.3 mg/kg per day . | FFS + PDN ≤0.2 mg/kg per day . | FFS + PDN ≤0.1 mg/kg per day . |
All patients | 304 (100) | 0.56 | 0.40 | 0.25 | 0.14 |
Low | 66 (22) | 0.67 | 0.55 | 0.35 | 0.20 |
Intermediate | 139 (46) | 0.59 | 0.40 | 0.28 | 0.14 |
High | 99 (33) | 0.44 | 0.24 | 0.11 | 0.07 |
. | . | Success rates at 6 mo . | |||
---|---|---|---|---|---|
Risk group* . | N (%) . | FFS . | FFS + PDN ≤0.3 mg/kg per day . | FFS + PDN ≤0.2 mg/kg per day . | FFS + PDN ≤0.1 mg/kg per day . |
All patients | 304 (100) | 0.56 | 0.40 | 0.25 | 0.14 |
Low | 66 (22) | 0.67 | 0.55 | 0.35 | 0.20 |
Intermediate | 139 (46) | 0.59 | 0.40 | 0.28 | 0.14 |
High | 99 (33) | 0.44 | 0.24 | 0.11 | 0.07 |
This analysis excluded 4 patients who did not have information for NIH global severity score and 4 patients who had FFS at 6 mo with information missing for steroid dose at 6 mo.
PDN, prednisone-equivalent steroid dose.
The low-risk group included patients with no risk factors, the intermediate-risk group included those with 1 risk factor, and the high-risk group included those with 2 or 3 risk factors. Risk factors included high-risk disease at transplantation, lower gastrointestinal involvement at second-line treatment, and severe NIH global score at second-line treatment.