Table 2.

Clinical and hematological features of patients receiving a diagnosis of ICUS grouped according to mutation status compared with features of patients receiving a diagnosis of MDS

VariableICUSMDSP value
ICUS unmutatedCCUS low predictive patternCCUS high predictive pattern
No. of patients 97 24 32 233  
Age, median (range), y 53 (18-88) 68 (18-86) 68 (41-86) 69 (27-91) <.001 
Sex, M/F 44/53 12/9 25/11 142/91 .012 
Hemoglobin, median (range), g/dL 12.7 (8.6-15.7) 12.9 (9.7-15.4) 11.9 (8.2-14.8) 9.9 (5-15.6) <.001 
Mean cell volume, median (range), fL 92 (78-110) 92 (82-102) 92 (78-118) 98 (63-124) <.001 
White blood cell count, median (range), ×109/L 3.72 (0.96-12.4) 3.72 (1.75-9.5) 3.94 (0.56-12.2) 4.26 (0.7-15.82) .72 
Absolute neutrophil count, median (range), ×109/L 1.85 (0.68-9.2) 1.88 (0.61-5.67) 1.70 (0.61-6.22) 2.4 (0.18-12.62) .89 
Platelet count, median (range), ×109/L 151 (20-496) 117 (71-206) 137 (23-355) 129 (6-495) .46 
VariableICUSMDSP value
ICUS unmutatedCCUS low predictive patternCCUS high predictive pattern
No. of patients 97 24 32 233  
Age, median (range), y 53 (18-88) 68 (18-86) 68 (41-86) 69 (27-91) <.001 
Sex, M/F 44/53 12/9 25/11 142/91 .012 
Hemoglobin, median (range), g/dL 12.7 (8.6-15.7) 12.9 (9.7-15.4) 11.9 (8.2-14.8) 9.9 (5-15.6) <.001 
Mean cell volume, median (range), fL 92 (78-110) 92 (82-102) 92 (78-118) 98 (63-124) <.001 
White blood cell count, median (range), ×109/L 3.72 (0.96-12.4) 3.72 (1.75-9.5) 3.94 (0.56-12.2) 4.26 (0.7-15.82) .72 
Absolute neutrophil count, median (range), ×109/L 1.85 (0.68-9.2) 1.88 (0.61-5.67) 1.70 (0.61-6.22) 2.4 (0.18-12.62) .89 
Platelet count, median (range), ×109/L 151 (20-496) 117 (71-206) 137 (23-355) 129 (6-495) .46 
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