Table 2 Venous thrombosis prediction... | American Society of Hematology

Table 2

Venous thrombosis prediction using genetic, nongenetic, and combined risk scores

	MEGA (N = 7092)		LETS (N = 881)
	AUC (95% CI)	Nagelkerke pseudo r²	AUC (95% CI)	Nagelkerke pseudo r²
31-SNP risk score	0.71 (0.69-0.72)	0.161	0.69 (0.65-0.72)	0.149
5-SNP risk score	0.69 (0.67-0.70)	0.135	0.67 (0.64-0.71)	0.138
Nongenetic risk score	0.77 (0.76-0.78)	0.288	0.71 (0.68-0.74)	0.200
Combined risk score	0.82 (0.81-0.83)	0.378	0.77 (0.74-0.80)	0.292

	MEGA (N = 7092)		LETS (N = 881)
	AUC (95% CI)	Nagelkerke pseudo r²	AUC (95% CI)	Nagelkerke pseudo r²
31-SNP risk score	0.71 (0.69-0.72)	0.161	0.69 (0.65-0.72)	0.149
5-SNP risk score	0.69 (0.67-0.70)	0.135	0.67 (0.64-0.71)	0.138
Nongenetic risk score	0.77 (0.76-0.78)	0.288	0.71 (0.68-0.74)	0.200
Combined risk score	0.82 (0.81-0.83)	0.378	0.77 (0.74-0.80)	0.292

The LETS study was used as a validation set.