Table 1

Kinetic parameters of binding of C1q, gC1q, and gC1qR to DC-SIGN

AnalyteKD, M
C1q 1.87 × 10−7 
gC1q 9.6 × 10−6 
gC1qR 40 × 10−6 
AnalyteKD, M
C1q 1.87 × 10−7 
gC1q 9.6 × 10−6 
gC1qR 40 × 10−6 

SPR analysis of C1q, monomeric gC1q, and gC1qR binding to immobilized DC-SIGN was performed. Protein at the indicated concentrations was injected through the DC-SIGN–immobilized flow cells.

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