Table 2 New recurrent copy number... | American Society of Hematology

Table 2

New recurrent copy number alterations

Genomic lesion	Paired patients, n	Unpaired patients, n	Frequency within cohort	Start	Stop	Segment length	Genes
del(15)(q15.1)	1*	7†	4%	39 745 774	39 816 254	70 480	MGA
del(10)(q24)	2*	4*	2%	104 146 465	105 040 096	893 631	19 genes (eg, NFKB2)
del(14)(q24.3)	2	3‡	2%	75 152 557	75 614 215	461 658	FLVCR2, C14orf1, TTLL5, BCYRN1, TGFB3, C14orf179
del(1)(q23.3)	2	1	1%	158 997 196	159 441 807	444 611	19 genes
del(1)(q42.12)	2	1	1%	223 854 863	224 490 349	635 486	12 genes
del(3)(p21.31)	2	2	1%	47 565 887	49 821 882	1 255 995	58 genes (eg, ATRIP)
del(6)(p22.1)	3	2	1%	26 121 993	26 343 281	221 288	Histone cluster, HFE
gain(6)(p25.3)	2	1	1%	94 649	1 485 307	1 390 658	DUSP22, IRF4, EXOC2, HUS1B, LOC285768, FOXQ1, FOXF2
del(9)(q13-q21.11)	2	3	1%	70 139 836	70 788 159	648 323	PGM5, C9orf71, PIP5K1B
del(14)(q13.2)	2		1%	34 107 436	35 183 612	1 076 176	11 genes (eg, NFKBIA)

Genomic lesion	Paired patients, n	Unpaired patients, n	Frequency within cohort	Start	Stop	Segment length	Genes
del(15)(q15.1)	1*	7†	4%	39 745 774	39 816 254	70 480	MGA
del(10)(q24)	2*	4*	2%	104 146 465	105 040 096	893 631	19 genes (eg, NFKB2)
del(14)(q24.3)	2	3‡	2%	75 152 557	75 614 215	461 658	FLVCR2, C14orf1, TTLL5, BCYRN1, TGFB3, C14orf179
del(1)(q23.3)	2	1	1%	158 997 196	159 441 807	444 611	19 genes
del(1)(q42.12)	2	1	1%	223 854 863	224 490 349	635 486	12 genes
del(3)(p21.31)	2	2	1%	47 565 887	49 821 882	1 255 995	58 genes (eg, ATRIP)
del(6)(p22.1)	3	2	1%	26 121 993	26 343 281	221 288	Histone cluster, HFE
gain(6)(p25.3)	2	1	1%	94 649	1 485 307	1 390 658	DUSP22, IRF4, EXOC2, HUS1B, LOC285768, FOXQ1, FOXF2
del(9)(q13-q21.11)	2	3	1%	70 139 836	70 788 159	648 323	PGM5, C9orf71, PIP5K1B
del(14)(q13.2)	2		1%	34 107 436	35 183 612	1 076 176	11 genes (eg, NFKBIA)

Loss in close vicinity in 1 patient.

Losses in close vicinity in 5 different patients.

Losses in close vicinity in 2 different patients.