Table 1

Myeloid maturation in bone marrow

MyeloblastNeutrophil maturation, % of all counted cells
MonocyteLymphocyte
PromyelocyteMyelocyteMetamyelocyteSegmented
Wt 4 ± 1 2 ± 0.3 12 ± 1 12 ± 2 31 ± 4 6 ± 1 21 ± 5 
Gfi1−/− 4 ± 1 0.2 ± 0.2 4 ± 1* 2 ± 1* 2 ± 2* 54 ± 12* 10 ± 2* 
Gfi136N/36N 2 ± 2 3 ± 1 6 ± 2 10 ± 2 25 ± 3 19 ± 3 31 ± 3 
Gfi136S/36S 2 ± 1 1 ± 1 14 ± 7 10 ± 1 16 ± 5 14 ± 3 37 ± 3 
MyeloblastNeutrophil maturation, % of all counted cells
MonocyteLymphocyte
PromyelocyteMyelocyteMetamyelocyteSegmented
Wt 4 ± 1 2 ± 0.3 12 ± 1 12 ± 2 31 ± 4 6 ± 1 21 ± 5 
Gfi1−/− 4 ± 1 0.2 ± 0.2 4 ± 1* 2 ± 1* 2 ± 2* 54 ± 12* 10 ± 2* 
Gfi136N/36N 2 ± 2 3 ± 1 6 ± 2 10 ± 2 25 ± 3 19 ± 3 31 ± 3 
Gfi136S/36S 2 ± 1 1 ± 1 14 ± 7 10 ± 1 16 ± 5 14 ± 3 37 ± 3 

Quantification of the different cell types according to their morphology enumerated from bone marrow cytospins of the indicated mouse strains (n = 3 for all genotypes).

*

Significant difference to wt mouse strain.

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