Clinical features of cases (N = 198)
Sex, n (%) | |
Female | 119 (60.1) |
Male | 79 (39.9) |
Ratio | 1.5 |
Age at diagnosis, y | |
Overall | |
Mean (SD) | 49.0 (18.2) |
Median | 50.8 |
Female (n = 119) | |
Mean (SD) | 45.4 (18.3) |
Median | 42.7 |
Male (n = 79) | |
Mean (SD) | 54.4 (16.8) |
Median | 57.3 |
Platelet count at diagnosis, G/L | |
Mean (SD) | 15.1 (17.1) |
Median (min-max) | 7.5 (0.0-87.0) |
At or below 50 G/L | 186 (94.4) |
Bleeding symptoms at diagnosis, n (%) | |
Epistaxis | 38 (19.2) |
Cutaneous bleeding | 154 (77.8) |
Bleeding from mucous membranes | 90 (45.5) |
Visceral hemorrhage | 8 (4.0) |
At least 1 bleeding symptom | 166 (83.8) |
Days from first symptom to recruitment, mean (SD) | 73.3 (90.1) |
Frontline treatment, n (%) | |
Corticosteroids | 159 (80.3) |
IV Ig | 100 (50.5) |
Other treatment | 14 (7.1) |
Overall initial response to treatment* | 164 (82.8) |
Sex, n (%) | |
Female | 119 (60.1) |
Male | 79 (39.9) |
Ratio | 1.5 |
Age at diagnosis, y | |
Overall | |
Mean (SD) | 49.0 (18.2) |
Median | 50.8 |
Female (n = 119) | |
Mean (SD) | 45.4 (18.3) |
Median | 42.7 |
Male (n = 79) | |
Mean (SD) | 54.4 (16.8) |
Median | 57.3 |
Platelet count at diagnosis, G/L | |
Mean (SD) | 15.1 (17.1) |
Median (min-max) | 7.5 (0.0-87.0) |
At or below 50 G/L | 186 (94.4) |
Bleeding symptoms at diagnosis, n (%) | |
Epistaxis | 38 (19.2) |
Cutaneous bleeding | 154 (77.8) |
Bleeding from mucous membranes | 90 (45.5) |
Visceral hemorrhage | 8 (4.0) |
At least 1 bleeding symptom | 166 (83.8) |
Days from first symptom to recruitment, mean (SD) | 73.3 (90.1) |
Frontline treatment, n (%) | |
Corticosteroids | 159 (80.3) |
IV Ig | 100 (50.5) |
Other treatment | 14 (7.1) |
Overall initial response to treatment* | 164 (82.8) |
Response was defined by a platelet count above 30 × 109/L with at least a 2-fold increase from pretreatment count.