Table 1

Clinical features of cases (N = 198)

Sex, n (%)  
    Female 119 (60.1) 
    Male 79 (39.9) 
    Ratio 1.5 
Age at diagnosis, y 
    Overall  
        Mean (SD) 49.0 (18.2) 
        Median 50.8 
    Female (n = 119) 
        Mean (SD) 45.4 (18.3) 
        Median 42.7 
    Male (n = 79) 
        Mean (SD) 54.4 (16.8) 
        Median 57.3 
Platelet count at diagnosis, G/L 
    Mean (SD) 15.1 (17.1) 
    Median (min-max) 7.5 (0.0-87.0) 
    At or below 50 G/L 186 (94.4) 
Bleeding symptoms at diagnosis, n (%) 
    Epistaxis 38 (19.2) 
    Cutaneous bleeding 154 (77.8) 
    Bleeding from mucous membranes 90 (45.5) 
    Visceral hemorrhage 8 (4.0) 
    At least 1 bleeding symptom 166 (83.8) 
Days from first symptom to recruitment, mean (SD) 73.3 (90.1) 
Frontline treatment, n (%) 
    Corticosteroids 159 (80.3) 
    IV Ig 100 (50.5) 
    Other treatment 14 (7.1) 
    Overall initial response to treatment* 164 (82.8) 
Sex, n (%)  
    Female 119 (60.1) 
    Male 79 (39.9) 
    Ratio 1.5 
Age at diagnosis, y 
    Overall  
        Mean (SD) 49.0 (18.2) 
        Median 50.8 
    Female (n = 119) 
        Mean (SD) 45.4 (18.3) 
        Median 42.7 
    Male (n = 79) 
        Mean (SD) 54.4 (16.8) 
        Median 57.3 
Platelet count at diagnosis, G/L 
    Mean (SD) 15.1 (17.1) 
    Median (min-max) 7.5 (0.0-87.0) 
    At or below 50 G/L 186 (94.4) 
Bleeding symptoms at diagnosis, n (%) 
    Epistaxis 38 (19.2) 
    Cutaneous bleeding 154 (77.8) 
    Bleeding from mucous membranes 90 (45.5) 
    Visceral hemorrhage 8 (4.0) 
    At least 1 bleeding symptom 166 (83.8) 
Days from first symptom to recruitment, mean (SD) 73.3 (90.1) 
Frontline treatment, n (%) 
    Corticosteroids 159 (80.3) 
    IV Ig 100 (50.5) 
    Other treatment 14 (7.1) 
    Overall initial response to treatment* 164 (82.8) 
*

Response was defined by a platelet count above 30 × 109/L with at least a 2-fold increase from pretreatment count.

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