CRLF2 rearrangement and JAK mutation status of xenografted ALL samples
| Xenograft no. . | TARGET ID/USI . | CRLF2 rearrangement . | JAK mutation . | Other lesions . | Ph-like . |
|---|---|---|---|---|---|
| I | 9906_151/PALKTY | P2RY8-CRLF2 | JAK2 QGinsR683 | Yes | |
| II | 9906_258/PAMDRM | IGH@-CRLF2 | JAK2 GPInsR683 | Yes | |
| III | 9906_020/PAKHZT | IGH@-CRLF2 | JAK2 R867Q | Yes | |
| IV | 9906_257/PAMDKS | IGH@-CRLF2 | JAK2 R683G | Yes | |
| V | 9906_037/PAKMVD | Negative | JAK1 S646F | Yes | |
| VI | 9906_196/PALTWS | IGH@-CRLF2 | Negative | No | |
| VII | 9906_084/PAKYEP | Negative | Negative | BCR-JAK2 | Yes |
| VIII | 9906_145/PALJDL | Negative | Negative | IL7R L242 > FPGVC, SH2B3 deletion | Yes |
| Xenograft no. . | TARGET ID/USI . | CRLF2 rearrangement . | JAK mutation . | Other lesions . | Ph-like . |
|---|---|---|---|---|---|
| I | 9906_151/PALKTY | P2RY8-CRLF2 | JAK2 QGinsR683 | Yes | |
| II | 9906_258/PAMDRM | IGH@-CRLF2 | JAK2 GPInsR683 | Yes | |
| III | 9906_020/PAKHZT | IGH@-CRLF2 | JAK2 R867Q | Yes | |
| IV | 9906_257/PAMDKS | IGH@-CRLF2 | JAK2 R683G | Yes | |
| V | 9906_037/PAKMVD | Negative | JAK1 S646F | Yes | |
| VI | 9906_196/PALTWS | IGH@-CRLF2 | Negative | No | |
| VII | 9906_084/PAKYEP | Negative | Negative | BCR-JAK2 | Yes |
| VIII | 9906_145/PALJDL | Negative | Negative | IL7R L242 > FPGVC, SH2B3 deletion | Yes |
ALL indicates acute lymphoblastic leukemia; TARGET, therapeutically applicable research to generate effective treatments; and USI, unique specimen identifer.