Additional data from the 45 patients with HbE β thalassemia, including ascorbate and iron status and levels of IL-8 and haptoglobin, including the different genetic forms of the latter
| Variable (units), normal range . | n . | Median . | Interquartile range . | Range . |
|---|---|---|---|---|
| Methemoglobin (%), 0.1-0.6 | 45 | 2.70 | 1.9-3.65 | 0.9-6.3 |
| Plasma ascorbate (nmol/mL), 28-84 | 20 | 28.23 | 21.03-31.68 | 12.6-56.3 |
| IL-8 (pg/mL), < 10 | 45 | 7.97 | 3.47-172.8 | 0.39-2210 |
| Hepatic iron (mg/g dw), 0.6-1.2 | 33 | 6.0 | 2.95-10.75 | 1.0-33.0 |
| Haptoglobin (g/L), 0.3-2.0 | ||||
| All cases | 38 | 0.24 | 0.20-0.28 | 0.16-0.42 |
| Haptoglobin genotype 1:1 | 0 | |||
| Haptoglobin genotype 2:1 | 8 | 0.27 | 0.26-0.33 | 0.22-0.33 |
| Haptoglobin genotype 2:2 | 25 | 0.23 | 0.19-0.26 | 0.16-0.41 |
| Variable (units), normal range . | n . | Median . | Interquartile range . | Range . |
|---|---|---|---|---|
| Methemoglobin (%), 0.1-0.6 | 45 | 2.70 | 1.9-3.65 | 0.9-6.3 |
| Plasma ascorbate (nmol/mL), 28-84 | 20 | 28.23 | 21.03-31.68 | 12.6-56.3 |
| IL-8 (pg/mL), < 10 | 45 | 7.97 | 3.47-172.8 | 0.39-2210 |
| Hepatic iron (mg/g dw), 0.6-1.2 | 33 | 6.0 | 2.95-10.75 | 1.0-33.0 |
| Haptoglobin (g/L), 0.3-2.0 | ||||
| All cases | 38 | 0.24 | 0.20-0.28 | 0.16-0.42 |
| Haptoglobin genotype 1:1 | 0 | |||
| Haptoglobin genotype 2:1 | 8 | 0.27 | 0.26-0.33 | 0.22-0.33 |
| Haptoglobin genotype 2:2 | 25 | 0.23 | 0.19-0.26 | 0.16-0.41 |
Hb indicates hemoglobin.