Further biochemical and related analyses of the propositus, including, in some cases, data obtained before and after treatment with vitamin C
| Variable (units), normal range . | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Treatment period . | Ascorbate (nmol/mL), 28-84 . | Met Hb (%), 0.1-0.6 . | P50 (mm Hg), 24.1-27.2 . | Mean Hb (g/dL), 12-16 . | Mean Epo (IU/mL), 2-14 . | G6PD (U/gHb), 4.6-13.5 . | Pyruvate kinase (IU/gHb), 7.2-14.0 . | GSH, (μmol/gHb), 6.6-10.0 . | Haptoglobin (g/dL), 0.3-2.0 . | Hepatic iron (mg/g dw), 0.6-1.2 . | IL-8, (pg/mL) < 10 . | Urinary, nitrite screen . |
| Pretreatment | 2.1-6.7 | 10.7-13.6 | 21.3-23.6 | 6.2 | 94.3 | 21.1 | 7.7 | 6.18 | 0.26 | 2.9 | 179.6 | Negative |
| Posttreatment | 30.2-36.6 | 0.85 | 26.9 | 7.0 | 76.8 | |||||||
| Variable (units), normal range . | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Treatment period . | Ascorbate (nmol/mL), 28-84 . | Met Hb (%), 0.1-0.6 . | P50 (mm Hg), 24.1-27.2 . | Mean Hb (g/dL), 12-16 . | Mean Epo (IU/mL), 2-14 . | G6PD (U/gHb), 4.6-13.5 . | Pyruvate kinase (IU/gHb), 7.2-14.0 . | GSH, (μmol/gHb), 6.6-10.0 . | Haptoglobin (g/dL), 0.3-2.0 . | Hepatic iron (mg/g dw), 0.6-1.2 . | IL-8, (pg/mL) < 10 . | Urinary, nitrite screen . |
| Pretreatment | 2.1-6.7 | 10.7-13.6 | 21.3-23.6 | 6.2 | 94.3 | 21.1 | 7.7 | 6.18 | 0.26 | 2.9 | 179.6 | Negative |
| Posttreatment | 30.2-36.6 | 0.85 | 26.9 | 7.0 | 76.8 | |||||||
Hb and Epo values are the means of 5 estimations.
Epo indicates erythropoietin; G6PD, glucose-6-phosphate dehydrogenase; Hb, hemoglobin; and Met, methemoglobin.