Table 1

Baseline demographic and clinical characteristics by CD25 expression in the 396 patients with detailed mutational analysis

CD25NEG (n = 316)CD25POS (n = 80)P
Age, y 47 (18-60) 46 (18-60) .39 
WBC, 1000/mm3 18.5 (0.6-212.8) 24.8 (1.0-181.0) .03 
Hemoglobin, g/dL 9.2 (5-30) 9.2 (5-11.7) .51 
Peripheral blasts, % 45 (0-98) 52.5 (0-92) .55 
Platelets, 1000/mm3 51 (0.7-650) 48 (1.4-261) .54 
Marrow blast 68 (3-100) 65 (8-99) .61 
Female sex, no. patients, % 146 (46) 43 (54) .26 
Cytogenetics favorable, no. patients, % 67 (23) 4 (5) < .001 
Cytogenetics intermediate, no. patients, % 171 (58) 63 (85)  
Cytogenetics unfavorable, no. patients, % 59 (20) 7 (10)  
CD25NEG (n = 316)CD25POS (n = 80)P
Age, y 47 (18-60) 46 (18-60) .39 
WBC, 1000/mm3 18.5 (0.6-212.8) 24.8 (1.0-181.0) .03 
Hemoglobin, g/dL 9.2 (5-30) 9.2 (5-11.7) .51 
Peripheral blasts, % 45 (0-98) 52.5 (0-92) .55 
Platelets, 1000/mm3 51 (0.7-650) 48 (1.4-261) .54 
Marrow blast 68 (3-100) 65 (8-99) .61 
Female sex, no. patients, % 146 (46) 43 (54) .26 
Cytogenetics favorable, no. patients, % 67 (23) 4 (5) < .001 
Cytogenetics intermediate, no. patients, % 171 (58) 63 (85)  
Cytogenetics unfavorable, no. patients, % 59 (20) 7 (10)  

All values are median (range) unless otherwise noted.

AML indicates acute myeloid leukemia; and WBC, white blood cell count.

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