Table 1

FY 2010 Extramural NHLBI projects by selected mechanisms that together accounted for 87% of all extramural funds

MechanismNonclinical projects
Clinical projects
No.Total funding (% extramural funding)Median cost per project (25th, 75th percentiles)No.Total funding (% extramural funding)Median cost per project (25th and 75th percentiles)
Contract 86 155 399 (6%) 1717 (522, 2274) 68 65 479 (3%) 378 (109, 1018) 
P01 120 187 232 (7%) 1752 (1018, 2116) 33 57 204 (2%) 1945 (1570, 2423) 
P50 1734 (< 1%) — 21 42 449 (2%) 2247 (1619, 2594) 
R01 2475 804 079 (33%) 381 (364, 410) 995 515 239 (21%) 431 (375, 672) 
R21 263 37 610 (2%) 213 (191, 231) 71 14 664 (< 1%) 199 (189, 228) 
R44 50 27 958 (1%) 500 (373, 681) 34 26 727 (1%) 647 (420, 998) 
U01 37 31 756 (1%) 1092 (345, 1311) 236 181 620 (7%) 472 (159, 948) 
MechanismNonclinical projects
Clinical projects
No.Total funding (% extramural funding)Median cost per project (25th, 75th percentiles)No.Total funding (% extramural funding)Median cost per project (25th and 75th percentiles)
Contract 86 155 399 (6%) 1717 (522, 2274) 68 65 479 (3%) 378 (109, 1018) 
P01 120 187 232 (7%) 1752 (1018, 2116) 33 57 204 (2%) 1945 (1570, 2423) 
P50 1734 (< 1%) — 21 42 449 (2%) 2247 (1619, 2594) 
R01 2475 804 079 (33%) 381 (364, 410) 995 515 239 (21%) 431 (375, 672) 
R21 263 37 610 (2%) 213 (191, 231) 71 14 664 (< 1%) 199 (189, 228) 
R44 50 27 958 (1%) 500 (373, 681) 34 26 727 (1%) 647 (420, 998) 
U01 37 31 756 (1%) 1092 (345, 1311) 236 181 620 (7%) 472 (159, 948) 

All costs are in units of $1000. All data were obtained from the publicly available NIH Research Portfolio Online Reporting Tools (RePORT). Estimates of funding for various RCDCs are at http://report.nih.gov/categorical_spending.aspx. Clinical projects are those categorized in RCDC as “Clinical Research” or “Clinical Trials.” Total NHLBI extramural funding in FY10 was $2 441 772 050. Values for numbers of projects, total funding for each mechanism, and median (25th, 75th percentiles) costs per project were calculated using the SAS Version 9.2 “Proc Tabulate” procedure.

P01 indicates Program Project Grant; P50, Research Center Grant; —, not applicable; R01, Research Project Grant; R21, Exploratory/Developmental Research Grant; R44, Small Business Innovation Research Grant; and U01, Research Project Cooperative Agreement.