Functional clustering of differentially expressed genes in Smo-depleted OP9
| Category term* . | Feature† . | Count‡ . | Enrichment score§ . |
|---|---|---|---|
| Glycoprotein | Glycosylation, signal peptide, extracellular region | 116 | 10.25 |
| Pattern recognition | Polysaccharide, heparin, pattern binding | 14 | 4.45 |
| Extracellular matrix | Extracellular region and matrix | 28 | 3.72 |
| Cell adhesion | Biological, cell, and cell-cell adhesion | 21 | 3.16 |
| Oxidation reduction | Oxidation reduction and oxidoreductase | 22 | 3.08 |
| Category term* . | Feature† . | Count‡ . | Enrichment score§ . |
|---|---|---|---|
| Glycoprotein | Glycosylation, signal peptide, extracellular region | 116 | 10.25 |
| Pattern recognition | Polysaccharide, heparin, pattern binding | 14 | 4.45 |
| Extracellular matrix | Extracellular region and matrix | 28 | 3.72 |
| Cell adhesion | Biological, cell, and cell-cell adhesion | 21 | 3.16 |
| Oxidation reduction | Oxidation reduction and oxidoreductase | 22 | 3.08 |
DAVID functional clustering26,27 was performed on 264 genes (206 down-regulated, 58 up-regulated) displaying a 2-fold or greater change with P < .001.
General DAVID functional category.
General DAVID functional annotation term.
Number of genes indentified in functional cluster.
Enrichment score was determined by EASE.26,27