Laboratory evaluation of study patients
| Pt. no. . | Hgb (12.6-16.1 g/dL) . | Albumin (2.7-3.7 g/dL) . | MGUS . | Paraprotein level, g/dL . | Free LC ratio (κ/λ, 0.38-1.78) . | β2 microglobulin (0.9-1.7 mg/L) . | CRP (< 0.8 mg/dL) . | ESR (0-25 mm/h) . |
|---|---|---|---|---|---|---|---|---|
| 1 | 15.2 | 3.6 | IgG κ | 0.3 | 0.87 | 2.9 | 1.54 | 7 |
| 2 | 11.7 | 3.5 | IgG κ | 0.7 | 3.35 | 2.5 | 7.97 | 14 |
| 3 | 18.5 | 3.7 | IgA κ | Below quant | 0.54 | 1.8 | 3.18 | ND |
| 4 | 15 | 4.1 | IgG κ | 0.6 | ND | 1.9 | ND | ND |
| 5 | 13.1 | 3.7 | IgG λ | 0.4 | 0.3 | 3.7 | < 0.4 | 3 |
| 6 | 15.2 | 3.6 | IgG κ | 0.3 | 0.87 | 2.9 | 1.54 | 7 |
| 7 | 15.1 | 4.1 | IgG κ | 0.7 | 1.9 | 1.4 | < 0.4 | 2 |
| 8 | 4.1 | 14.7 | IgG κ | 0.4 | 0.96 | 1.8 | 1.7 | 11 |
| 9 | 3.9 | 15.2 | IgG κ | 0.3 | 1.21 | 1.9 | 1.03 | 7 |
| 10 | 11.8 | 3.9 | None | 0.7 | 1.6 | 21 | ||
| 11 | 13.7 | 4.4 | IgG λ | Undetectable | ND | 1.6 | 1.55 | 7 |
| 12 | 15.8 | 3.5 | IgG κ | 0.2 | 1.31 | 1.7 | < 0.16 | 2 |
| 13 | 14.4 | 4.2 | IgG κ | 0.5 | 3.23 | 2.4 | < 0.16 | 31 |
| 14 | 13.9 | 3.8 | Present, unknown isotype | Undetectable | 0.74 | 1.2 | ||
| 15 | 13.6 | 2.7 | IgG λ | Below quant | 1.05 | 10.4 | 65 | |
| 16 | 13.8 | 3.6 | IgG κ | 0.7 | 5.33 | 2.2 | 0.98 | 2 |
| 17 | 13.9 | 4.1 | IgG κ | 0.7 | 1.2 | 3.3 | 25.3 | 29 |
| 18 | 13.4 | 3.7 | Present, unknown isotype | Below quant | 1.55 | 4.5 | 5 | |
| 19 | 11.7 | 3.6 | IgG λ | Below quant | 2.01 | 2.1 | 8.75 | 8 |
| 20 | 15.7 | 3.5 | IgG κ | Below quant | 1.1 | 1.5 | 1.3 | 2 |
| 21 | 15.5 | 4.2 | IgG κ | Below quant | 1.35 | 1.6 | 0.68 | 2 |
| 22 | 12.7 | 3.8 | IgG κ | 0.5 | 2.44 | 1.2 | 0.32 | 2 |
| 23 | 14.2 | 4.0 | IgG κ | 0.3 | 1.8 | 2.38 | 2 |
| Pt. no. . | Hgb (12.6-16.1 g/dL) . | Albumin (2.7-3.7 g/dL) . | MGUS . | Paraprotein level, g/dL . | Free LC ratio (κ/λ, 0.38-1.78) . | β2 microglobulin (0.9-1.7 mg/L) . | CRP (< 0.8 mg/dL) . | ESR (0-25 mm/h) . |
|---|---|---|---|---|---|---|---|---|
| 1 | 15.2 | 3.6 | IgG κ | 0.3 | 0.87 | 2.9 | 1.54 | 7 |
| 2 | 11.7 | 3.5 | IgG κ | 0.7 | 3.35 | 2.5 | 7.97 | 14 |
| 3 | 18.5 | 3.7 | IgA κ | Below quant | 0.54 | 1.8 | 3.18 | ND |
| 4 | 15 | 4.1 | IgG κ | 0.6 | ND | 1.9 | ND | ND |
| 5 | 13.1 | 3.7 | IgG λ | 0.4 | 0.3 | 3.7 | < 0.4 | 3 |
| 6 | 15.2 | 3.6 | IgG κ | 0.3 | 0.87 | 2.9 | 1.54 | 7 |
| 7 | 15.1 | 4.1 | IgG κ | 0.7 | 1.9 | 1.4 | < 0.4 | 2 |
| 8 | 4.1 | 14.7 | IgG κ | 0.4 | 0.96 | 1.8 | 1.7 | 11 |
| 9 | 3.9 | 15.2 | IgG κ | 0.3 | 1.21 | 1.9 | 1.03 | 7 |
| 10 | 11.8 | 3.9 | None | 0.7 | 1.6 | 21 | ||
| 11 | 13.7 | 4.4 | IgG λ | Undetectable | ND | 1.6 | 1.55 | 7 |
| 12 | 15.8 | 3.5 | IgG κ | 0.2 | 1.31 | 1.7 | < 0.16 | 2 |
| 13 | 14.4 | 4.2 | IgG κ | 0.5 | 3.23 | 2.4 | < 0.16 | 31 |
| 14 | 13.9 | 3.8 | Present, unknown isotype | Undetectable | 0.74 | 1.2 | ||
| 15 | 13.6 | 2.7 | IgG λ | Below quant | 1.05 | 10.4 | 65 | |
| 16 | 13.8 | 3.6 | IgG κ | 0.7 | 5.33 | 2.2 | 0.98 | 2 |
| 17 | 13.9 | 4.1 | IgG κ | 0.7 | 1.2 | 3.3 | 25.3 | 29 |
| 18 | 13.4 | 3.7 | Present, unknown isotype | Below quant | 1.55 | 4.5 | 5 | |
| 19 | 11.7 | 3.6 | IgG λ | Below quant | 2.01 | 2.1 | 8.75 | 8 |
| 20 | 15.7 | 3.5 | IgG κ | Below quant | 1.1 | 1.5 | 1.3 | 2 |
| 21 | 15.5 | 4.2 | IgG κ | Below quant | 1.35 | 1.6 | 0.68 | 2 |
| 22 | 12.7 | 3.8 | IgG κ | 0.5 | 2.44 | 1.2 | 0.32 | 2 |
| 23 | 14.2 | 4.0 | IgG κ | 0.3 | 1.8 | 2.38 | 2 |
Laboratory reference values are indicated in parentheses.
Pt indicates patient; MGUS, monoclonal gammopathy of unknown significance; LC, light chain; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; quant, quantification; and ND, not done.