Influence of measurement interval on the fold rise
| Measurement interval group* . | No. of measurements† (no. with BC relapse) . | Fold rise, median (range) . | P . | Doubling time, median (range) . | P . |
|---|---|---|---|---|---|
| ≤ 30 days | 27 (1) | 5.2 (2.1-51) | < .0001 | 8.7 (4.9-18.9) | .32 |
| 31-60 days | 16 (3) | 15.7 (3.0-383) | 10.0 (5.3-26.5) | ||
| 61-93 days‡ | 13 (8) | 101 (4.9-2400) | 9.6 (7.7-26.9) |
| Measurement interval group* . | No. of measurements† (no. with BC relapse) . | Fold rise, median (range) . | P . | Doubling time, median (range) . | P . |
|---|---|---|---|---|---|
| ≤ 30 days | 27 (1) | 5.2 (2.1-51) | < .0001 | 8.7 (4.9-18.9) | .32 |
| 31-60 days | 16 (3) | 15.7 (3.0-383) | 10.0 (5.3-26.5) | ||
| 61-93 days‡ | 13 (8) | 101 (4.9-2400) | 9.6 (7.7-26.9) |
The difference between the median number of days of each of the measurement interval groups was significant (P < .0001).
For patients with consecutive measurements during the rise (n = 15), data from both measurement intervals were included.
Only 1 patient had a measurement interval more than 90 days and was included in the third group.