The ratio of red pulp/white pulp and percentage of red pulp in control and PHZ-treated WT and Dhh−/− spleen
. | Red pulp/white pulp . | Red pulp, % . | ||
---|---|---|---|---|
WT . | Dhh−/− . | WT . | Dhh−/− . | |
Day 0 | 1.4 | 2.1 | 59 | 68 |
Day 5 | 5.2 | 4.8 | 84 | 83 |
Day 7 | 4.8 | 6.2 | 83 | 86 |
Day 9 | 5.0 | 4.9 | 83 | 83 |
Day 14 | 3.7 | 2.5 | 79 | 71 |
. | Red pulp/white pulp . | Red pulp, % . | ||
---|---|---|---|---|
WT . | Dhh−/− . | WT . | Dhh−/− . | |
Day 0 | 1.4 | 2.1 | 59 | 68 |
Day 5 | 5.2 | 4.8 | 84 | 83 |
Day 7 | 4.8 | 6.2 | 83 | 86 |
Day 9 | 5.0 | 4.9 | 83 | 83 |
Day 14 | 3.7 | 2.5 | 79 | 71 |
Red pulp and white pulp and entire surface area of longitudinal sections of paraffin-embedded spleen from WT and Dhh−/− mice, untreated (day 0), and at time points after PHZ treatment. Ratio of red pulp and white pulp and percentage of red pulp were quantified using ImageJ software.