Table 1

The ratio of red pulp/white pulp and percentage of red pulp in control and PHZ-treated WT and Dhh−/− spleen

Red pulp/white pulp
Red pulp, %
WTDhh−/−WTDhh−/−
Day 0 1.4 2.1 59 68 
Day 5 5.2 4.8 84 83 
Day 7 4.8 6.2 83 86 
Day 9 5.0 4.9 83 83 
Day 14 3.7 2.5 79 71 
Red pulp/white pulp
Red pulp, %
WTDhh−/−WTDhh−/−
Day 0 1.4 2.1 59 68 
Day 5 5.2 4.8 84 83 
Day 7 4.8 6.2 83 86 
Day 9 5.0 4.9 83 83 
Day 14 3.7 2.5 79 71 

Red pulp and white pulp and entire surface area of longitudinal sections of paraffin-embedded spleen from WT and Dhh−/− mice, untreated (day 0), and at time points after PHZ treatment. Ratio of red pulp and white pulp and percentage of red pulp were quantified using ImageJ software.

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