Table 2

Response evaluation 0.24 mg/kg/d cohort by treatment indication (N = 46)

NResponses
Treatment failure
Response rate, %
CRCRiPersistent leukemiaDeath during aplasiaUnknownCR + CRiCR only
First relapse, first salvage, total 32 15 12 56 47 
    CR1 < 6 mo 11 27 18 
    First salvage, CR1 6-12 mo 11 64 45 
    First salvage, CR1 > 12 mo 10 80 80 
Primary refractory, total 10 20 20 
    1 induction 25 25 
    ≥ 2 inductions 
≥ Second relapse /salvage 25 25 
Total 46 18 21 46 39 
NResponses
Treatment failure
Response rate, %
CRCRiPersistent leukemiaDeath during aplasiaUnknownCR + CRiCR only
First relapse, first salvage, total 32 15 12 56 47 
    CR1 < 6 mo 11 27 18 
    First salvage, CR1 6-12 mo 11 64 45 
    First salvage, CR1 > 12 mo 10 80 80 
Primary refractory, total 10 20 20 
    1 induction 25 25 
    ≥ 2 inductions 
≥ Second relapse /salvage 25 25 
Total 46 18 21 46 39 

CRi indicates complete remission with incomplete blood count recovery.

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