Time-dependent multivariable cause-specific Cox regression analysis of influence on NRM
| Covariate . | P . | HR . | 95% CI . |
|---|---|---|---|
| Donor | |||
| RD vs MUD | .04 | 8.0 | 1.10-56.8 |
| RD vs MMUD | .0001 | 19.7 | 4.2-91.4 |
| Conditioning | |||
| RIC vs MAC | .15 | 0.31 | 0.1-1.5 |
| disease score | |||
| 0 vs 1 | .80 | 1.15 | 0.5-2.9 |
| sFASL (cut-off, 50 pg/mL) | .0001 | 0.05 | 0.01-0.18 |
| ANG2/VEGF (cut-off, 10) | .0004 | 17.5 | 3.5-87.1 |
| Covariate . | P . | HR . | 95% CI . |
|---|---|---|---|
| Donor | |||
| RD vs MUD | .04 | 8.0 | 1.10-56.8 |
| RD vs MMUD | .0001 | 19.7 | 4.2-91.4 |
| Conditioning | |||
| RIC vs MAC | .15 | 0.31 | 0.1-1.5 |
| disease score | |||
| 0 vs 1 | .80 | 1.15 | 0.5-2.9 |
| sFASL (cut-off, 50 pg/mL) | .0001 | 0.05 | 0.01-0.18 |
| ANG2/VEGF (cut-off, 10) | .0004 | 17.5 | 3.5-87.1 |
Covariates included: ANG2/VEGF (< 10 vs 10), FASL (< 50 pg/mL vs > 50 pg/mL), donor (RD vs MUD vs MMUD), conditioning (RIC vs MAC), and disease score (0 vs 1 vs 2). Serum parameters were measured before SCT, at escalation of immunosuppression, and in the follow-up period.
RR indicates relative risk.