Hematological and iron parameters in wild-type ID mice and Tmprss6−/− mice before and after injection of LPS
| . | ID . | ID + LPS . | Tmprss6−/− . | Tmprss6−/− + LPS . |
|---|---|---|---|---|
| RBC, ×1012/L | 9.6 ± 0.31 | 8.93 ± 0.37 | 9.44 ± 1.19 | 9.02 ± 0.18 |
| Hgb, g/L | 126 ± 4.4 | 121 ± 14 | 97 ± 15.5* | 91 ± 3.8 |
| Hct, % | 42.64 ± 2.34 | 38.71 ± 1.24 | 39.1 ± 2.75* | 34.37 ± 0.97 |
| MCV, ×10−15/L | 44.37 ± 1.11 | 43.3 ± 0.79 | 38.6 ± 1.56* | 38.4 ± 1.1 |
| MCH, pg | 13.13 ± 0.06 | 13.5 ± 1.04 | 10.2 ± 0.42† | 10.1 ± 0.26 |
| WBC, ×109/L | 10.64 ± 1.55 | 1.83 ± 1.03 | 9.25 ± 1.14 | 2.68 ± 0.74 |
| TS, % | 17.36 ± 0.26 | 12.69 ± 2.5* | 13.02 ± 2.86 | 11.71 ± 0.96 |
| . | ID . | ID + LPS . | Tmprss6−/− . | Tmprss6−/− + LPS . |
|---|---|---|---|---|
| RBC, ×1012/L | 9.6 ± 0.31 | 8.93 ± 0.37 | 9.44 ± 1.19 | 9.02 ± 0.18 |
| Hgb, g/L | 126 ± 4.4 | 121 ± 14 | 97 ± 15.5* | 91 ± 3.8 |
| Hct, % | 42.64 ± 2.34 | 38.71 ± 1.24 | 39.1 ± 2.75* | 34.37 ± 0.97 |
| MCV, ×10−15/L | 44.37 ± 1.11 | 43.3 ± 0.79 | 38.6 ± 1.56* | 38.4 ± 1.1 |
| MCH, pg | 13.13 ± 0.06 | 13.5 ± 1.04 | 10.2 ± 0.42† | 10.1 ± 0.26 |
| WBC, ×109/L | 10.64 ± 1.55 | 1.83 ± 1.03 | 9.25 ± 1.14 | 2.68 ± 0.74 |
| TS, % | 17.36 ± 0.26 | 12.69 ± 2.5* | 13.02 ± 2.86 | 11.71 ± 0.96 |
Mean hematological and iron parameters in ID and Tmprss6−/− mice.
ID indicates iron deficient; LPS, lipopolysaccharide; Hgb, hemoglobin; Hct, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; WBC, white blood cell; and TS, transferrin saturation.
P < .05 (vs ID mice).
P < .001 (vs ID mice).