Association of missing HLA alleles with AA in Japanese patients
| Risk allele . | AA (N = 407) . | Other diseases (N = 6206) . | Total (N = 6613) . | P (χ2 test) . | Odds ratio (95% CI) (vs no risk alleles) . |
|---|---|---|---|---|---|
| A*02:01 | 103 | 1173 | 1276 | 2.5 × 10−6 | 1.87 (1.43−2.43) |
| A*02:06 | 100 | 957 | 1057 | < 1.0 × 10−7 | 2.22 (1.70−2.90) |
| A*31:01 | 58 | 899 | 957 | 0.048 | 1.37 (1.00−1.88) |
| B*40:02 | 86 | 938 | 1024 | 1.8 × 10−6 | 1.95 (1.48−2.58) |
| All risk alleles | 268 | 3250 | 3518 | 1.3 × 10−7 | 1.75 (1.42−2.17) |
| No risk alleles | 139 | 2956 | 3095 | — | — |
| Risk allele . | AA (N = 407) . | Other diseases (N = 6206) . | Total (N = 6613) . | P (χ2 test) . | Odds ratio (95% CI) (vs no risk alleles) . |
|---|---|---|---|---|---|
| A*02:01 | 103 | 1173 | 1276 | 2.5 × 10−6 | 1.87 (1.43−2.43) |
| A*02:06 | 100 | 957 | 1057 | < 1.0 × 10−7 | 2.22 (1.70−2.90) |
| A*31:01 | 58 | 899 | 957 | 0.048 | 1.37 (1.00−1.88) |
| B*40:02 | 86 | 938 | 1024 | 1.8 × 10−6 | 1.95 (1.48−2.58) |
| All risk alleles | 268 | 3250 | 3518 | 1.3 × 10−7 | 1.75 (1.42−2.17) |
| No risk alleles | 139 | 2956 | 3095 | — | — |
— indicates not applicable.