Table 3

Summary of characteristics of RXL- and GA101-induced cell death in CD40-stimulated CLL cells

CharacteristicRXLGA101
HA + ++ 
LMP − + 
Ca flux + − 
ROS + − 
MitoTracker + + 
Annexin V/PI + + 
Caspase activation + + 
Sub-G1 + + 
CharacteristicRXLGA101
HA + ++ 
LMP − + 
Ca flux + − 
ROS + − 
MitoTracker + + 
Annexin V/PI + + 
Caspase activation + + 
Sub-G1 + + 

+ indicates present; ++, clearly present; and −, absent.

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