Table 4

Multivariate analysis

Parameters in modelHR (95% CI)P
Survival reference (OS)*   
    IGHV mutation status (reference: M-CLL) 6.91 (1.92-24.87) .003 
    CL1HICL3LO (ref: all other groups combined) 5.26 (1.95-14.21) .001 
Treatment (TTFT)   
    IGHV mutation status (reference: M-CLL) 2.90 (1.36-6.19) .0059 
    CL1HICL2LO (reference: all other groups combined) 6.12 (2.48-15.10) < .0001 
Parameters in modelHR (95% CI)P
Survival reference (OS)*   
    IGHV mutation status (reference: M-CLL) 6.91 (1.92-24.87) .003 
    CL1HICL3LO (ref: all other groups combined) 5.26 (1.95-14.21) .001 
Treatment (TTFT)   
    IGHV mutation status (reference: M-CLL) 2.90 (1.36-6.19) .0059 
    CL1HICL2LO (reference: all other groups combined) 6.12 (2.48-15.10) < .0001 
*

OS indicates overall survival.

TTFT indicates time-to-first treatment.

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