Treatment strategy in frail patients with MM
| Specific characteristics . | Treatment . | Maintenance . |
|---|---|---|
| Absence of renal failure | Lenalidomide based | Low-dose lenalidomide |
| No aggressive disease | ||
| Presence of peripheral neuropathy | ||
| Difficult access to hospital | ||
| Presence of renal failure | Bortezomib based | Twice-monthly subcutaneous bortezomib |
| Aggressive disease | ||
| Presence of extramedullary disease | ||
| Easy access to hospital |
| Specific characteristics . | Treatment . | Maintenance . |
|---|---|---|
| Absence of renal failure | Lenalidomide based | Low-dose lenalidomide |
| No aggressive disease | ||
| Presence of peripheral neuropathy | ||
| Difficult access to hospital | ||
| Presence of renal failure | Bortezomib based | Twice-monthly subcutaneous bortezomib |
| Aggressive disease | ||
| Presence of extramedullary disease | ||
| Easy access to hospital |