Assigned variable-specific risk scores for each category of the variables selected based on relative risk
| Variable . | Risk score . |
|---|---|
| Recipient age at transplantation | |
| < 29 y | 0 |
| 30-59 y | 1 |
| > 60 y | 2 |
| Prior acute GVHD | |
| None | 0 |
| Present | 1 |
| Time from transplantation to cGVHD | |
| ≥ 5 mo | 0 |
| < 5 mo | 1 |
| Serum bilirubin at cGVHD onset | |
| ≤ 2 mg/dL | 0 |
| > 2 mg/dL | 2 |
| KPS at cGVHD onset | |
| ≥ 80 | 0 |
| < 80 | 1 |
| Platelet count at cGVHD onset | |
| < 100 × 109/L | 1 |
| ≥ 100 × 109/L | 0 |
| Type of donor | |
| HLA-identical sibling/well-matched or partially matched URD | 0 |
| Other related/mismatched URD | 1 |
| Disease status at transplantation | |
| Early | 0 |
| Intermediate | 1 |
| Advanced | 2 |
| Sex mismatch (donor/recipient) | |
| Male/ male, male/female, female/female | 0 |
| Female/male | 1 |
| GVHD prophylaxis | |
| CSA + MTX + other | 0 |
| Tacrolimus + MTX + other or T-cell depletion | 1 |
| Variable . | Risk score . |
|---|---|
| Recipient age at transplantation | |
| < 29 y | 0 |
| 30-59 y | 1 |
| > 60 y | 2 |
| Prior acute GVHD | |
| None | 0 |
| Present | 1 |
| Time from transplantation to cGVHD | |
| ≥ 5 mo | 0 |
| < 5 mo | 1 |
| Serum bilirubin at cGVHD onset | |
| ≤ 2 mg/dL | 0 |
| > 2 mg/dL | 2 |
| KPS at cGVHD onset | |
| ≥ 80 | 0 |
| < 80 | 1 |
| Platelet count at cGVHD onset | |
| < 100 × 109/L | 1 |
| ≥ 100 × 109/L | 0 |
| Type of donor | |
| HLA-identical sibling/well-matched or partially matched URD | 0 |
| Other related/mismatched URD | 1 |
| Disease status at transplantation | |
| Early | 0 |
| Intermediate | 1 |
| Advanced | 2 |
| Sex mismatch (donor/recipient) | |
| Male/ male, male/female, female/female | 0 |
| Female/male | 1 |
| GVHD prophylaxis | |
| CSA + MTX + other | 0 |
| Tacrolimus + MTX + other or T-cell depletion | 1 |
CSA indicates cyclosporine; and MTX, methotrexate.