Analysis of the 80 genes of the GEP80 model with the use of the Molecular Signature Database showing significant overlap with proteasome pathway–related gene sets
| Gene set name . | No. genes in gene set, K . | Description . | No. genes in overlap, k . | k/K . | P . |
|---|---|---|---|---|---|
| KEGG_PROTEASOME | 48 | Proteasome | 11 | 0.2292 | 6.52E-14 |
| BIOCARTA_PROTEASOME_PATHWAY | 19 | Proteasome complex | 6 | 0.3158 | 1.59E-13 |
| WONG_PROTEASOME_GENE_MODULE | 46 | Genes that comprise the proteasome gene module | 7 | 0.1522 | 3.77E-13 |
| PROTEASOME_COMPLEX | 23 | Genes annotated by the GO term GO:0000502, a large multiple subunit complex that catalyzes protein degradation. This complex consists of the barrel-shaped proteasome core complex and 1 or 2 associated proteins or complexes that act in regulating entry into or exit from the core. | 5 | 0.2174 | 1.55E-10 |
| Gene set name . | No. genes in gene set, K . | Description . | No. genes in overlap, k . | k/K . | P . |
|---|---|---|---|---|---|
| KEGG_PROTEASOME | 48 | Proteasome | 11 | 0.2292 | 6.52E-14 |
| BIOCARTA_PROTEASOME_PATHWAY | 19 | Proteasome complex | 6 | 0.3158 | 1.59E-13 |
| WONG_PROTEASOME_GENE_MODULE | 46 | Genes that comprise the proteasome gene module | 7 | 0.1522 | 3.77E-13 |
| PROTEASOME_COMPLEX | 23 | Genes annotated by the GO term GO:0000502, a large multiple subunit complex that catalyzes protein degradation. This complex consists of the barrel-shaped proteasome core complex and 1 or 2 associated proteins or complexes that act in regulating entry into or exit from the core. | 5 | 0.2174 | 1.55E-10 |
Shown are the top 4 gene sets.
Overlaps were computed with gene sets C1, C3, C5, CPG, CP:Biocarta, and CP:KEGG.