Splenic CD4 T-cell gene expression analyzed by RT-PCR
| . | Controls (n = 6) . | RTX-untreated ITP patients (n = 4) . | RTX-treated ITP patients (n = 5) . | P . |
|---|---|---|---|---|
| Foxp3 | 9.3 ± 5.1 | 1.9 ± 2.5 | 1.5 ± 0.8 | .017 |
| T-bet | 831.8 ± 464.4 | 432.9 ± 228.2 | 448.0 ± 233.1 | .18 |
| IFN-γ | 667.0 ± 395.5 | 1449 ± 1062 | 1222 ± 530.7 | .25 |
| GATA3 | 1290 ± 721.4 | 407.6 ± 68.3 | 1312 ± 855.3 | .06 |
| RORc | 569.7 ± 550.5 | 155.0 ± 96.2 | 322.8 ± 198.3 | .31 |
| IL-17A | 184.0 ± 112.1 | 175.4 ± 79.3 | 266.4 ± 190.8 | .76 |
| IFN-γ/Foxp3 | 80.7 ± 58.2 | 3850 ± 5374 | 1113 ± 538 | .013 |
| . | Controls (n = 6) . | RTX-untreated ITP patients (n = 4) . | RTX-treated ITP patients (n = 5) . | P . |
|---|---|---|---|---|
| Foxp3 | 9.3 ± 5.1 | 1.9 ± 2.5 | 1.5 ± 0.8 | .017 |
| T-bet | 831.8 ± 464.4 | 432.9 ± 228.2 | 448.0 ± 233.1 | .18 |
| IFN-γ | 667.0 ± 395.5 | 1449 ± 1062 | 1222 ± 530.7 | .25 |
| GATA3 | 1290 ± 721.4 | 407.6 ± 68.3 | 1312 ± 855.3 | .06 |
| RORc | 569.7 ± 550.5 | 155.0 ± 96.2 | 322.8 ± 198.3 | .31 |
| IL-17A | 184.0 ± 112.1 | 175.4 ± 79.3 | 266.4 ± 190.8 | .76 |
| IFN-γ/Foxp3 | 80.7 ± 58.2 | 3850 ± 5374 | 1113 ± 538 | .013 |
Results are expressed as means ± SD and are expressed in arbitrary units. P values derived by Kruskal-Wallis test.