Summary of clinical data for Hb-SS subjects
| Subject no. . | Sex . | Age, y . | Hb, g/dL . | Hb F, % . | MCV, fL . | Reticulocytes, × 109/L (%) . | WBCs, × 109/L . | Platelets, × 109/L . |
|---|---|---|---|---|---|---|---|---|
| SCD 1 | F | 25 | 9.4 | 5.3 | 85 | 235 (6.9) | 9.6 | 356 |
| SCD 2 | M | 34 | 8.6 | NDd | 92 | 351 (12.5) | 10.1 | 265 |
| SCD 3 | F | 23 | 7.9 | ND | 86 | 261 (9.6) | 7.8 | 377 |
| SCD 4 | F | 28 | 9.4 | 6.2 | 93 | 351 (12.5) | 11.2 | 380 |
| SCD 5 | M | 20 | 11.4 | 10.4 | 89 | 250 (6.8) | 11.1 | 505 |
| SCD 6 | M | 29 | 8.1 | ND | 90 | ND | 11.2 | 504 |
| SCD 7 | F | 24 | 10.2 | 9.9 | 88 | 214 (6.1) | 9.7 | 499 |
| SCD 8 | M | 38 | 11.1 | 15.9 | 109 | ND | 12.4 | 275 |
| SCD 9 | F | 55 | 8.1 | ND | 91 | ND | 7.9 | 164 |
| SCD 10 | M | 26 | 9.7 | 1.6 | 70 | 205 (4.7) | 13.5 | 496 |
| SCD 11 | F | 40 | 8.7 | ND | 100 | 174 (6.7) | 9.3 | 349 |
| SCD 12 | M | 28 | 9 | ND | 85 | 229 (7.4) | 12.2 | 389 |
| SCD 13 | F | 19 | 9.1 | 12.7 | 99 | 296 (11) | 14.4 | 628 |
| SCD 14 | M | 46 | 7.3 | 5.9 | 90 | 323 (14) | 9.3 | 288 |
| SCD 15 | M | 27 | 8.2 | 0.9 | 75 | 139 (4.2) | 6.4 | 256 |
| SCD 16 | M | 38 | 6.1 | ND | 93 | 218 (11.4) | 12.8 | 292 |
| SCD 17 | M | 34 | 8.6 | ND | 92 | 351 (12.5) | 10.1 | 265 |
| SCD 18 | M | 45 | 10.5 | ND | 84 | 216 (5.7) | 8.9 | 263 |
| SCD 19 | F | 46 | 9.3 | 11.2 | 89 | 231 (7.2) | 12.4 | 379 |
| SCD 20 | M | 39 | 7.7 | ND | 81 | 448 (16) | 11.3 | 259 |
| SCD 21 | M | 33 | 11.2 | 9 | 83 | 228 (5.4) | 9.3 | 262 |
| SCD 22 | F | 28 | 9.5 | 8.8 | 85 | 336 (9.9) | 12.9 | 389 |
| SCD 23 | M | 31 | 11.3 | ND | 83 | 184 (4.4) | 7.8 | 317 |
| SCD 24 | M | 33 | 8.9 | 6.7 | 87 | 163 (5.2) | 8.0 | 299 |
| SCD 25 | F | 38 | 7.6 | 2.9 | 90 | 224 (9.3) | 11.6 | 359 |
| SCD 26 | F | 42 | 9.6 | ND | 110 | 210 (8.2) | 10.1 | 445 |
| SCD 27 | M | 46 | 10.5 | 1.7 | 80 | 350 (8.5) | 7.8 | 275 |
| SCD 28 | F | 44 | 8.2 | ND | 108 | 249 (11.3) | 13.9 | 422 |
| Subject no. . | Sex . | Age, y . | Hb, g/dL . | Hb F, % . | MCV, fL . | Reticulocytes, × 109/L (%) . | WBCs, × 109/L . | Platelets, × 109/L . |
|---|---|---|---|---|---|---|---|---|
| SCD 1 | F | 25 | 9.4 | 5.3 | 85 | 235 (6.9) | 9.6 | 356 |
| SCD 2 | M | 34 | 8.6 | NDd | 92 | 351 (12.5) | 10.1 | 265 |
| SCD 3 | F | 23 | 7.9 | ND | 86 | 261 (9.6) | 7.8 | 377 |
| SCD 4 | F | 28 | 9.4 | 6.2 | 93 | 351 (12.5) | 11.2 | 380 |
| SCD 5 | M | 20 | 11.4 | 10.4 | 89 | 250 (6.8) | 11.1 | 505 |
| SCD 6 | M | 29 | 8.1 | ND | 90 | ND | 11.2 | 504 |
| SCD 7 | F | 24 | 10.2 | 9.9 | 88 | 214 (6.1) | 9.7 | 499 |
| SCD 8 | M | 38 | 11.1 | 15.9 | 109 | ND | 12.4 | 275 |
| SCD 9 | F | 55 | 8.1 | ND | 91 | ND | 7.9 | 164 |
| SCD 10 | M | 26 | 9.7 | 1.6 | 70 | 205 (4.7) | 13.5 | 496 |
| SCD 11 | F | 40 | 8.7 | ND | 100 | 174 (6.7) | 9.3 | 349 |
| SCD 12 | M | 28 | 9 | ND | 85 | 229 (7.4) | 12.2 | 389 |
| SCD 13 | F | 19 | 9.1 | 12.7 | 99 | 296 (11) | 14.4 | 628 |
| SCD 14 | M | 46 | 7.3 | 5.9 | 90 | 323 (14) | 9.3 | 288 |
| SCD 15 | M | 27 | 8.2 | 0.9 | 75 | 139 (4.2) | 6.4 | 256 |
| SCD 16 | M | 38 | 6.1 | ND | 93 | 218 (11.4) | 12.8 | 292 |
| SCD 17 | M | 34 | 8.6 | ND | 92 | 351 (12.5) | 10.1 | 265 |
| SCD 18 | M | 45 | 10.5 | ND | 84 | 216 (5.7) | 8.9 | 263 |
| SCD 19 | F | 46 | 9.3 | 11.2 | 89 | 231 (7.2) | 12.4 | 379 |
| SCD 20 | M | 39 | 7.7 | ND | 81 | 448 (16) | 11.3 | 259 |
| SCD 21 | M | 33 | 11.2 | 9 | 83 | 228 (5.4) | 9.3 | 262 |
| SCD 22 | F | 28 | 9.5 | 8.8 | 85 | 336 (9.9) | 12.9 | 389 |
| SCD 23 | M | 31 | 11.3 | ND | 83 | 184 (4.4) | 7.8 | 317 |
| SCD 24 | M | 33 | 8.9 | 6.7 | 87 | 163 (5.2) | 8.0 | 299 |
| SCD 25 | F | 38 | 7.6 | 2.9 | 90 | 224 (9.3) | 11.6 | 359 |
| SCD 26 | F | 42 | 9.6 | ND | 110 | 210 (8.2) | 10.1 | 445 |
| SCD 27 | M | 46 | 10.5 | 1.7 | 80 | 350 (8.5) | 7.8 | 275 |
| SCD 28 | F | 44 | 8.2 | ND | 108 | 249 (11.3) | 13.9 | 422 |
F indicates female; M, male; Hb, hemoglobin; MCV, mean corpuscular volume; WBCs, white blood cells; and ND, not determined.