Surrogate and clinical responses to imatinib
Patient no. . | Response (last follow-up) . | Prednisone, mg/d . | Lee symptom score . | Imatinib (mg/day) at last follow-up . | Duration of therapy, wk . | ||
---|---|---|---|---|---|---|---|
Baseline . | Last follow-up . | Baseline . | Last follow-up . | ||||
1 | Stable disease | 15 | 0 | 10 | 9 | 400 | 72 |
2 | Minor | 5 | 15 | 28 | 4 | 400 | 25 |
3 | Progressive disease | 20 | 25 | 31 | 30 | 400 | 19.1 |
4 | Minor | 25 | 5 | 29 | 37 | 300 | 38.1 |
6 | Major | 40 | 7.5 | 11 | 2 | 200 | 75.7 |
7 | Minor | 20 | 0 | 73 | 22 | 400 | 79.7 |
8 | Major | 17.5 | 15 | 21 | 3 | 400 | 72 |
10 | Stable disease | 30 | 10 | 29 | 16 | 200 | 55.4 |
11 | Progressive disease | 5 | 30 | 29 | 37 | 200 | 56.6 |
12 | Major | 15 | 7.5 | 31 | 28 | 200 | 31.6 |
15 | Stable disease | 15 | 12.5 | 20 | 19 | 400 | 53.1 |
Patient no. . | Response (last follow-up) . | Prednisone, mg/d . | Lee symptom score . | Imatinib (mg/day) at last follow-up . | Duration of therapy, wk . | ||
---|---|---|---|---|---|---|---|
Baseline . | Last follow-up . | Baseline . | Last follow-up . | ||||
1 | Stable disease | 15 | 0 | 10 | 9 | 400 | 72 |
2 | Minor | 5 | 15 | 28 | 4 | 400 | 25 |
3 | Progressive disease | 20 | 25 | 31 | 30 | 400 | 19.1 |
4 | Minor | 25 | 5 | 29 | 37 | 300 | 38.1 |
6 | Major | 40 | 7.5 | 11 | 2 | 200 | 75.7 |
7 | Minor | 20 | 0 | 73 | 22 | 400 | 79.7 |
8 | Major | 17.5 | 15 | 21 | 3 | 400 | 72 |
10 | Stable disease | 30 | 10 | 29 | 16 | 200 | 55.4 |
11 | Progressive disease | 5 | 30 | 29 | 37 | 200 | 56.6 |
12 | Major | 15 | 7.5 | 31 | 28 | 200 | 31.6 |
15 | Stable disease | 15 | 12.5 | 20 | 19 | 400 | 53.1 |
Patients 5, 9, 13, and 14 were not evaluable for clinical response.