Table 3

Pharmacokinetic parameters of mAb 37surr in cynomolgus monkey

Parameter0.01 mg/kg0.3 mg/kg10 mg/kg
C(max) [μg/mL]/[mg/kg] NC 24.9 24.1 
AUC, 0-804 h [μg [times] h/mL]/[mg/kg] NC 140 1720 
t(1/2) [h] NC 5.7 ∼ 60 
Parameter0.01 mg/kg0.3 mg/kg10 mg/kg
C(max) [μg/mL]/[mg/kg] NC 24.9 24.1 
AUC, 0-804 h [μg [times] h/mL]/[mg/kg] NC 140 1720 
t(1/2) [h] NC 5.7 ∼ 60 

AUC indicates area under the curve; and NC, not calculated.

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