Table 2 Relative risk of HL associated... | American Society of Hematology

Table 2

Relative risk of HL associated with cART use and duration derived from Poisson regression

Cohort strata by use of and time on cART	No. of HL cases by strata	Incidence per 1000 PYs by strata	Model 0 crude RR (95%CI) P = .006	Model 1 adjusted RR (95%CI)*P = .005	Model 2 adjusted RR (95%CI)†P = .14	Model 3 adjusted RR (95%CI)‡P = .22
No cART and year < 1996	43	0.58	1.35 (0.84-2.18)	1.14 (0.7-1.85)	0.68 (0.4-1.17)
No cART and year ≥ 1996	28	0.79	1	1	1	1
≤ 3 months	15	1.69	2.95 (1.64-5.31)	2.61 (1.44-4.72)	1.42 (0.76-2.66)	1.40 (0.70-2.83)
4-6 months	8	0.94	1.63 (0.76-3.46)	1.43 (0.67-3.06)	0.90 (0.42-1.95)	0.82 (0.35-1.36)
> 6 months	93	0.58	1.00 (0.69-1.43)	0.83 (0.57-1.2)	0.75 (0.51-1.1)	0.73 (0.45-1.17)

Cohort strata by use of and time on cART	No. of HL cases by strata	Incidence per 1000 PYs by strata	Model 0 crude RR (95%CI) P = .006	Model 1 adjusted RR (95%CI)*P = .005	Model 2 adjusted RR (95%CI)†P = .14	Model 3 adjusted RR (95%CI)‡P = .22
No cART and year < 1996	43	0.58	1.35 (0.84-2.18)	1.14 (0.7-1.85)	0.68 (0.4-1.17)
No cART and year ≥ 1996	28	0.79	1	1	1	1
≤ 3 months	15	1.69	2.95 (1.64-5.31)	2.61 (1.44-4.72)	1.42 (0.76-2.66)	1.40 (0.70-2.83)
4-6 months	8	0.94	1.63 (0.76-3.46)	1.43 (0.67-3.06)	0.90 (0.42-1.95)	0.82 (0.35-1.36)
> 6 months	93	0.58	1.00 (0.69-1.43)	0.83 (0.57-1.2)	0.75 (0.51-1.1)	0.73 (0.45-1.17)

Adjusted for age, sex and exposure group, migration from sub-Saharan Africa, and AIDS stage.

Adjusted for variables in Model 1 and for CD4 cell count.

Adjusted for variables in Model 2 and for plasma HIV RNA, which was not available until 1997.