Table 3 Correlation of demographic and... | American Society of Hematology

Table 3

Correlation of demographic and clinicopathological parameters with Gal-1 expression in HRS cells and in the tumor microenvironment

Characteristic	Total no.	%	HRS Gal-1			Non-HRS Gal-1, cell profile Gal-1 count/mm²
Characteristic	Total no.	%	Gal-1 neg	Gal-1 pos	P†	Median	P‡
	143
Age, y (n = 143)
< 45	91	64	46	45	.11	1361	.27
≥ 45	52	36	19	33		1496
Sex (n = 143)
Male	92	64	43	49	.68	1387	.30
Female	51	36	22	29		1361
Ann Arbor stage (n = 143)
I-II	57	40	23	34	.32	1511	.62
III-IV	86	60	42	44		1358
B symptoms (n = 143)
Yes	117	82	46	71	.002	1482	.03
No	26	18	19	7		1138
Bulky disease, > 10 cm (n = 135)*
Yes	49	36	23	26	.76	1228	.20
No	86	64	38	48		1377
Histologic type (n = 143)
NSI	78	55	37	41	.03	1523	.49
NSII	42	29	13	29		1302
MC	22	15	15	7		1387
cHL, NOS	1	1	0	1		1523
IPS (n = 125)*
≤ 2	68	54	36	32	.11	1369	.51
> 2	57	46	22	35		1361
EBV status (n = 143)
Positive	48	34	28	20	.03	1345	.54
Negative	95	66	37	58		1384

Characteristic	Total no.	%	HRS Gal-1			Non-HRS Gal-1, cell profile Gal-1 count/mm²
Characteristic	Total no.	%	Gal-1 neg	Gal-1 pos	P†	Median	P‡
	143
Age, y (n = 143)
< 45	91	64	46	45	.11	1361	.27
≥ 45	52	36	19	33		1496
Sex (n = 143)
Male	92	64	43	49	.68	1387	.30
Female	51	36	22	29		1361
Ann Arbor stage (n = 143)
I-II	57	40	23	34	.32	1511	.62
III-IV	86	60	42	44		1358
B symptoms (n = 143)
Yes	117	82	46	71	.002	1482	.03
No	26	18	19	7		1138
Bulky disease, > 10 cm (n = 135)*
Yes	49	36	23	26	.76	1228	.20
No	86	64	38	48		1377
Histologic type (n = 143)
NSI	78	55	37	41	.03	1523	.49
NSII	42	29	13	29		1302
MC	22	15	15	7		1387
cHL, NOS	1	1	0	1		1523
IPS (n = 125)*
≤ 2	68	54	36	32	.11	1369	.51
> 2	57	46	22	35		1361
EBV status (n = 143)
Positive	48	34	28	20	.03	1345	.54
Negative	95	66	37	58		1384

NSI indicates nodular sclerosis type I; NSII, nodular sclerosis type II; MC, mixed cellularity; NOS, not otherwise specified; and IPS, international prognostic score.

Parameter not available in all 143 patients.

†

χ² test.

‡

Wilcoxon rank-sum test or Kruskal-Wallis equality-of-populations rank test where appropriate.

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