Secondary transplants (tested 4 months later) from primary recipients of α4Δ/Δ BM cells (at 10 weeks after primary transplantation)
. | . | Peripheral blood . | . | . | Bone marrow . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Donor cells 0.5 × 106 . | No. of recipients . | WBC × 106/μL . | CFU-C/mL . | Percent α4+ cells . | No. cells/femur × 106 . | CFU-C/femur × 103 . | Percent α4+ cells . | ||||
| α4+/+ (n = 3) | 5 | 2.15 ± 0.08 | 20 ± 5.8 | 95.7 ± 0.3 | 14.1 ± 0.5 | 20.3 ± 1.8 | 99.2 ± 0.1 | ||||
| α4Δ/Δ (n = 2) | 5 | 2.29 ± 0.36 | 30 ± 7.0 | 27.5 ± 4.7 | 10.0 ± 1.6 | 9.7* ± 2.7 | 19.0† ± 6.0 | ||||
| [α4+/α4–] (n = 1) | 5 | 2.17 ± 0.47 | 10 ± 4.1 | 58.0 ± 8.4 | 10.2 ± 2.5 | 14.3 ± 8.0 | 75.8 ± 8.2‡ | ||||
. | . | Peripheral blood . | . | . | Bone marrow . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Donor cells 0.5 × 106 . | No. of recipients . | WBC × 106/μL . | CFU-C/mL . | Percent α4+ cells . | No. cells/femur × 106 . | CFU-C/femur × 103 . | Percent α4+ cells . | ||||
| α4+/+ (n = 3) | 5 | 2.15 ± 0.08 | 20 ± 5.8 | 95.7 ± 0.3 | 14.1 ± 0.5 | 20.3 ± 1.8 | 99.2 ± 0.1 | ||||
| α4Δ/Δ (n = 2) | 5 | 2.29 ± 0.36 | 30 ± 7.0 | 27.5 ± 4.7 | 10.0 ± 1.6 | 9.7* ± 2.7 | 19.0† ± 6.0 | ||||
| [α4+/α4–] (n = 1) | 5 | 2.17 ± 0.47 | 10 ± 4.1 | 58.0 ± 8.4 | 10.2 ± 2.5 | 14.3 ± 8.0 | 75.8 ± 8.2‡ | ||||