Table 2.

Characteristics of CD19R+ T cells from UCB obtained after transplantation


UPN

Electroporated TNCs, no.

TNCs infused, %

Western blot chimeric CD3ζ (66 kDa)

Cytotoxicity by CRA with CD19+ target 5:1, %

Cytotoxicity by CRA with CD19- target 5:1, %
001   6.6 × 106  0.45   +   59   15  
002   4.0 × 106  0.78   +   39   1  
003
 
1.6 × 107
 
1.73
 
+
 
47
 
14
 

UPN

Electroporated TNCs, no.

TNCs infused, %

Western blot chimeric CD3ζ (66 kDa)

Cytotoxicity by CRA with CD19+ target 5:1, %

Cytotoxicity by CRA with CD19- target 5:1, %
001   6.6 × 106  0.45   +   59   15  
002   4.0 × 106  0.78   +   39   1  
003
 
1.6 × 107
 
1.73
 
+
 
47
 
14
 

UPN indicates unique patient number; TNCs, total nucleated cells.

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