Characteristics of CD19R+ T cells from UCB obtained after transplantation
UPN . | Electroporated TNCs, no. . | TNCs infused, % . | Western blot chimeric CD3ζ (66 kDa) . | Cytotoxicity by CRA with CD19+ target 5:1, % . | Cytotoxicity by CRA with CD19- target 5:1, % . |
|---|---|---|---|---|---|
| 001 | 6.6 × 106 | 0.45 | + | 59 | 15 |
| 002 | 4.0 × 106 | 0.78 | + | 39 | 1 |
| 003 | 1.6 × 107 | 1.73 | + | 47 | 14 |
UPN . | Electroporated TNCs, no. . | TNCs infused, % . | Western blot chimeric CD3ζ (66 kDa) . | Cytotoxicity by CRA with CD19+ target 5:1, % . | Cytotoxicity by CRA with CD19- target 5:1, % . |
|---|---|---|---|---|---|
| 001 | 6.6 × 106 | 0.45 | + | 59 | 15 |
| 002 | 4.0 × 106 | 0.78 | + | 39 | 1 |
| 003 | 1.6 × 107 | 1.73 | + | 47 | 14 |
UPN indicates unique patient number; TNCs, total nucleated cells.