Table 1

Peripheral blood cell counts and serum EPO levels

WTΔHmga2P
WBCs, ×109/L 8.10 ± 2.11 9.55 ± 2.34 .0315 
Neutrophils, ×109/L 1.31 ± 0.65 1.79 ± 0.78 .0331 
Monocytes, ×109/L 0.37 ± 0.21 0.62 ± 0.31 .0023 
Lymphocytes, ×109/L 6.38 ± 1.60 7.09 ± 2.23 .21 
Platelets, ×109/L 822 ± 81 880 ± 94 .0136 
RBCs, ×1012/L 9.14 ± 0.50 9.76 ± 0.44 .0001 
Hemoglobin, g/dL 13.0 ± 1.1 13.7 ± 2.0 .16 
Hematocrit, % 46.1 ± 3.8 46.8 ± 2.7 .49 
MCV, fL 50.6 ± 4.8 47.9 ± 2.5 .0189 
Reticulocytes, ×1012/L 0.56 ± 0.13 0.58 ± 0.11 .59 
EPO, pg/mL* 202 ± 65 125 ± 55 .0176 
WTΔHmga2P
WBCs, ×109/L 8.10 ± 2.11 9.55 ± 2.34 .0315 
Neutrophils, ×109/L 1.31 ± 0.65 1.79 ± 0.78 .0331 
Monocytes, ×109/L 0.37 ± 0.21 0.62 ± 0.31 .0023 
Lymphocytes, ×109/L 6.38 ± 1.60 7.09 ± 2.23 .21 
Platelets, ×109/L 822 ± 81 880 ± 94 .0136 
RBCs, ×1012/L 9.14 ± 0.50 9.76 ± 0.44 .0001 
Hemoglobin, g/dL 13.0 ± 1.1 13.7 ± 2.0 .16 
Hematocrit, % 46.1 ± 3.8 46.8 ± 2.7 .49 
MCV, fL 50.6 ± 4.8 47.9 ± 2.5 .0189 
Reticulocytes, ×1012/L 0.56 ± 0.13 0.58 ± 0.11 .59 
EPO, pg/mL* 202 ± 65 125 ± 55 .0176 

Peripheral blood cell counts (n = 29) and serum EPO levels (n = 8) were determined in 2-month-old ΔHmga2 mice and compared with age- and sex-matched WT mice (n = 22 for hematologic parameters and n = 10 for serum EPO values).

WBCs indicates white blood cells; RBCs, red blood cells; MCV, mean corpuscular volume; and EPO, erythropoietin.

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