Peripheral blood cell counts and serum EPO levels
. | WT . | ΔHmga2 . | P . |
---|---|---|---|
WBCs, ×109/L | 8.10 ± 2.11 | 9.55 ± 2.34 | .0315 |
Neutrophils, ×109/L | 1.31 ± 0.65 | 1.79 ± 0.78 | .0331 |
Monocytes, ×109/L | 0.37 ± 0.21 | 0.62 ± 0.31 | .0023 |
Lymphocytes, ×109/L | 6.38 ± 1.60 | 7.09 ± 2.23 | .21 |
Platelets, ×109/L | 822 ± 81 | 880 ± 94 | .0136 |
RBCs, ×1012/L | 9.14 ± 0.50 | 9.76 ± 0.44 | .0001 |
Hemoglobin, g/dL | 13.0 ± 1.1 | 13.7 ± 2.0 | .16 |
Hematocrit, % | 46.1 ± 3.8 | 46.8 ± 2.7 | .49 |
MCV, fL | 50.6 ± 4.8 | 47.9 ± 2.5 | .0189 |
Reticulocytes, ×1012/L | 0.56 ± 0.13 | 0.58 ± 0.11 | .59 |
EPO, pg/mL* | 202 ± 65 | 125 ± 55 | .0176 |
. | WT . | ΔHmga2 . | P . |
---|---|---|---|
WBCs, ×109/L | 8.10 ± 2.11 | 9.55 ± 2.34 | .0315 |
Neutrophils, ×109/L | 1.31 ± 0.65 | 1.79 ± 0.78 | .0331 |
Monocytes, ×109/L | 0.37 ± 0.21 | 0.62 ± 0.31 | .0023 |
Lymphocytes, ×109/L | 6.38 ± 1.60 | 7.09 ± 2.23 | .21 |
Platelets, ×109/L | 822 ± 81 | 880 ± 94 | .0136 |
RBCs, ×1012/L | 9.14 ± 0.50 | 9.76 ± 0.44 | .0001 |
Hemoglobin, g/dL | 13.0 ± 1.1 | 13.7 ± 2.0 | .16 |
Hematocrit, % | 46.1 ± 3.8 | 46.8 ± 2.7 | .49 |
MCV, fL | 50.6 ± 4.8 | 47.9 ± 2.5 | .0189 |
Reticulocytes, ×1012/L | 0.56 ± 0.13 | 0.58 ± 0.11 | .59 |
EPO, pg/mL* | 202 ± 65 | 125 ± 55 | .0176 |
Peripheral blood cell counts (n = 29) and serum EPO levels (n = 8) were determined in 2-month-old ΔHmga2 mice and compared with age- and sex-matched WT mice (n = 22 for hematologic parameters and n = 10 for serum EPO values).
WBCs indicates white blood cells; RBCs, red blood cells; MCV, mean corpuscular volume; and EPO, erythropoietin.