Table 1 TF activity and thrombin... | American Society of Hematology

Table 1

TF activity and thrombin generation supported by HSVECs, SMCs, and TNF-α-HSVECs

	HSVECs	SMCs	TNF-α-HSVECs*
TF activity
Without HTF1, pM/min	0.073 ± 0.012	12.08 ± 0.443†	3.141 ± 0.459†
With HTF1, pM/min	0.075 ± 0.007	0.973 ± 0.021	0.066 ± 0.066
Thrombin generation
Lag time, minutes	41.9 ± 12.1	2.7 ± 0.2†	6.1 ± 1.7†
Rate, nM/min	11.5 ± 5.0	77.1 ± 16.6†	21.0 ± 1.7†
Time to peak, minutes	48.0 ± 11.6	6.8 ± 0.6†	11.6 ± 1.3†
Peak height, nM	54.1 ± 21.6	274.5 ± 48.6†	113.9 ± 10.9†

	HSVECs	SMCs	TNF-α-HSVECs*
TF activity
Without HTF1, pM/min	0.073 ± 0.012	12.08 ± 0.443†	3.141 ± 0.459†
With HTF1, pM/min	0.075 ± 0.007	0.973 ± 0.021	0.066 ± 0.066
Thrombin generation
Lag time, minutes	41.9 ± 12.1	2.7 ± 0.2†	6.1 ± 1.7†
Rate, nM/min	11.5 ± 5.0	77.1 ± 16.6†	21.0 ± 1.7†
Time to peak, minutes	48.0 ± 11.6	6.8 ± 0.6†	11.6 ± 1.3†
Peak height, nM	54.1 ± 21.6	274.5 ± 48.6†	113.9 ± 10.9†

HSVECs treated with 100 ng/mL TNF-α for 6 hours.

P < .05 versus unstimulated HSVECs.