Clinical data and cell-activation potential of aPLAs*
. | Non–cell-activating aPLAs . | Cell-activating aPLAs . |
---|---|---|
Total | 13 | 19 |
APS | 13 | 18 |
SLE | 0 | 4 |
Thrombosis | 7 | 13 |
Fetal loss | 6 | 10 |
LA + aCL + β2GP1 | 3 | 8 |
LA + aCL | 2 | 4 |
LA + β2GP1 | 0 | 0 |
aCL + β2GP1 | 0 | 0 |
LA | 0 | 1 |
aCL | 8 | 6 |
β2GP1 | 0 | 0 |
. | Non–cell-activating aPLAs . | Cell-activating aPLAs . |
---|---|---|
Total | 13 | 19 |
APS | 13 | 18 |
SLE | 0 | 4 |
Thrombosis | 7 | 13 |
Fetal loss | 6 | 10 |
LA + aCL + β2GP1 | 3 | 8 |
LA + aCL | 2 | 4 |
LA + β2GP1 | 0 | 0 |
aCL + β2GP1 | 0 | 0 |
LA | 0 | 1 |
aCL | 8 | 6 |
β2GP1 | 0 | 0 |
aPLA indicates antiphospholipid antibody; SLE, systemic lupus erythematosus; LA, lupus anticoagulant; aCL, anti-cardiolipin IgG; and β2GP1, anti-β2GP1 IgG.
There was no significant association between cell-activation potential and patient characteristics or positivity in any particular aPLA assay.