CIS genes targeted multiple times (N Hits) within the integration datasets
| No. of hits . | Genes (interval in Kb) . |
|---|---|
| 4 | CARD8 (23), NSD1 (90), QRICH1 (31), SAPS2 (47), USP48 (48) |
| 5 | GPATCH8 (53) |
| 6 | FCHSD2 (272) |
| 7 | NPLOC4 (76), SMARCC1 (95), NF1 (140) |
| 8 | PACS1 (110), HLA (542) |
| 9 | FBXL11 (107) |
| No. of hits . | Genes (interval in Kb) . |
|---|---|
| 4 | CARD8 (23), NSD1 (90), QRICH1 (31), SAPS2 (47), USP48 (48) |
| 5 | GPATCH8 (53) |
| 6 | FCHSD2 (272) |
| 7 | NPLOC4 (76), SMARCC1 (95), NF1 (140) |
| 8 | PACS1 (110), HLA (542) |
| 9 | FBXL11 (107) |
The maximum distance between integrations targeting the same CIS is indicated. Note that only CIS genes targeted by ≥ 4 integrations are shown. With the exception of SAPS2 and USP48, all other CIS genes found in our experimental dataset matched the CISs of the ALD clinical trial. See supplemental Table 2 for further details on the identified CISs.